Recent clinical studies have shed new light on the diagnosis of venous thromboembolism. Pulmonary embolism continues to be difficult to diagnose because the definitive test, pulmonary angiography, is complex and not widely available. However, new knowledge about ventilation perfusion lung scanning and non-invasive leg studies can help to reduce the need for pulmonary angiography. Furthermore, t...

The assessment of clinical probability represents an important step in the diagnostic strategy of patients with suspected deep vein thrombosis. The recently derived LEFt clinical prediction rule for pregnant women combines three variables: symptoms in the left leg (L), calf circumference difference of 2 centimeters or over (E for edema) and first trimester presentation (Ft) but is lacking an ex...

The classical presentation of deep vein thrombosis (DVT) is sudden onset of pain, redness, and swelling of one leg spreading from the calf to the thigh with marked swelling of the dorsum of the foot and tenderness along the deep venous system. The more severe condition of ileofemoral thrombophlebitis can result in marked swelling and femoral arterial occlusion (plegmasia dolora albus). Fortunat...

PURPOSE We aimed to describe ultrasonography (US)-guided percutaneous aspiration thrombectomy in pregnant women with iliofemoral deep vein thrombosis. METHODS This study included nine pregnant women with acute and subacute iliofemoral deep vein thrombosis, who were severe symptomatic cases with massive swelling and pain of the leg. Patients were excluded from the study if they had only femoro...

Background:. Deep vein thrombosis and pulmonary embolism are rare complications of uterine myoma. There have been few reports on these associations. Case: A 41 year old para 1+0 presented with 20 weeks size fibroid uterus, which had compressed the pelvic veins and caused unilateral deep vein thrombosis of right leg with subsequent pulmonary embolism. After anticoagulation therapy, a total abdom...

OBJECTIVE To assess the clinical and economic consequences of a formulary switch from enoxaparin to dalteparin as first-line prophylaxis for deep-vein thrombosis in patients undergoing inpatient rehabilitation after total hip arthroplasty or total knee arthroplasty. DESIGN Retrospective cohort study. RESULTS There were 461 patients eligible for the study. The age-adjusted risk of a deep-vei...

BACKGROUND Factor V Leiden has been reported in 2%-30% of patients with portal vein thrombosis. This wide variation makes it difficult to assess the importance of factor V Leiden as a predisposing factor. METHODS Factor V Leiden was determined by restriction fragment length polymorphism in 112 patients with portal vein thrombosis, 104 with deep vein thrombosis and 98 control subjects. RESUL...

BACKGROUND A prospective clinical study was performed to compare the efficacy of low-molecular-weight heparin and indomethacin for the prevention of deep-vein thrombosis after total knee arthroplasty in Asian patients. METHODS One hundred and fifty patients undergoing total knee arthroplasty were randomly divided into three groups. One group consisted of fifty-one patients who received no pro...

INTRODUCTION The aims of this paper were to study the incidence of deep vein thrombosis following total knee replacement in an Asian population and to evaluate the role of low molecular weight heparin for deep vein thrombosis in this setting. MATERIALS AND METHODS We prospectively studied two groups of 100 consecutive patients undergoing total knee replacement separately. Group 1 did not rece...

In general medical patients presenting with suspected deep vein thrombosis routine use of x ray venography was associated with a large fall in the proportion of patients with a final diagnosis of deep vein thrombosis, from 83% to 25% (p less than 0.001), and with an appreciable shortening of hospital stay, from 13.6 to 7.2 days. The diagnosis of deep vein thrombosis was rejected in only 4% of p...