OBJECTIVE To perform comprehensive network and pathway analyses of the genes known to cause genetic hearing loss. STUDY DESIGN In silico analysis of deafness genes using ingenuity pathway analysis (IPA). METHODS Genes relevant for hearing and deafness were identified through PubMed literature searches and the Hereditary Hearing Loss Homepage. The genes were assembled into 3 groups: 63 genes...

Abstract The paper focuses on the question of whether it is morally permissible to use reproductive technologies select children with congenital deafness. I review arguments that have been presented support claims lack hearing not overall bad, disability caused by social discrimination rather than impairment, community deaf people gives its members plenty opportunities lead a happy life, and pr...

Altogether 153 (60%) out of a sample of 253 people aged 70 years and over living in their own homes were found to have impaired hearing when tested by pure-tone audiometry. This is almost twice the prevalence found in all other studies, in which deafness was assessed clinically or by self-reporting. The prevalence of deafness increased with age. Evidence of organic brain syndrome (dementia), as...

introduction: the aim of this study was to evaluate the efficacy of combined intratympanic and systemic steroid therapy compared with systemic steroid therapy alone in idiopathic sudden sensorineural hearing loss (issnhl) patients with poor prognostic factors.     materials and methods: seventy-seven patients with sudden sensorineural hearing loss (ssnhl) who had at least one poor prognostic fa...

The pure white cat with luminous blue eyes is an attractive image familiar to many. These animals are well-known to be commonly affected by a congenital hereditary deafness that may affect one or both ears; the deafness is linked to the so-called W gene. Reports of this condition date back to at least the 1930s (Bamber, 1933), and many investigators have studied it in subsequent years (Wolff, 1...