Featured Article: Nagatsu T and Udenfriend S. Photometric assay of dopamine-hydroxylase in human blood. Clin Chem 1972;18:980 –3. This report described a simple assay for measuring the activity of dopamine-hydroxylase (DBH) in human blood. DBH is a copper-containing, ascorbaterequiring glycoprotein enzyme that catalyzes the hydroxylation of dopamine to norepinephrine (NE), the precursor of epin...

We radiotracked 17 male northern long-eared bats (Myotis septentrionalis) to 43-day roosts and 23 females to 49-day roosts in the Ouachita Mountains of central Arkansas during summers 2000–2005. We compared characteristics of roost trees between males and females, and compared characteristics of sites surrounding roosts with random locations for each sex. Roosts were located in cavities, crevic...

The activity of serum dopamine-^-hydroxylase (DBH) was measured in 1194 asymptomatic middle-aged men with diastolic blood pressure ranging from 75 to 125 mm Hg during the baseline examination of a multifactorial intervention program for primary prevention of coronary heart disease. No correlation was present between serum DBH activity and systolic (r = 0.01, NS) or diastolic (r = + 0.02, NS) bl...

In this paper, we analyze the Hawking radiation (HR) of a non-asymptotically flat (NAF) dyonic black hole (dBH) in four-dimensional (4D) Einstein-Maxwell-Dilaton (EMD) gravity by using one of the semiclassical approaches which is the so-called Hamilton-Jacobi (HJ) method. We particularly motivate on the isotropic coordinate system (ICS) of the dBH in order to highlight the ambiguity to be appea...

The relationship between plasma norepinephrine (NE), epinephrine (E) and dopamine-beta-hydroxylase activity (DBH) was studied in 90 cardiac patients (New York Heart Association [NYHA] classes I-IV), 85 healthy control subjects and 18 competitive skiers. The cardiac patients in NYHA classes III and IV had significantly higher NE (p less than 0.001) and lower DBH (p less than 0.001) levels than t...

RATIONALE Dopamine β-hydroxylase (DBH) catalyzes the conversion of dopamine to norepinephrine in the central nervous system and peripherally. DBH variants are associated with large changes in circulating DBH and implicated in multiple disorders; yet causal relationships and tissue-specific effects remain unresolved. OBJECTIVE To characterize regulatory variants in DBH, effect on mRNA expressi...

Dopoamine-β-hydroxylase (DBH) is a catecholamine-synthesizing enzyme which catalyzes the formation of norepinephrine from dopamine. Fifty nine Long-Evans rats of 1 week-old were used to grow on normal diets in 7 different developmental stages, viz., 15 rats in 1 week-old group, 9 rats in 2 weeks-old group, and the remaining 35 rats were divided equally into five groups, 7 rats in each group of ...

Exogenous leptin enhances energy utilization in ob/ob mice by binding its hypothalamic receptor and selectively increasing peripheral fat oxidation. Leptin also increases uncoupling protein 1 (UCP1) expression in brown adipose tissue (BAT), but the neurotransmitter that mediates this effect has not been established. The present experiments sought to determine whether leptin regulates UCP1 expre...

Cerebrospinal fluid (CSF) and plasma dopamine-beta-hydroxylase (DBH) activity was measured in 22 normotensive (NT), 31 essential hypertensive (EH), and 11 renal hypertensive (RH) patients. Although no differences were observed in their plasma DBH, the mean CSF-DBH activity and specific activity of EH were significantly lower than those of NT and RH patients. Very low CSF-DBH (less than 0.15 uni...