DNA, whether it is microbe-derived or host-derived, evokes immune responses when exposed to the cytosol of a cell. We previously reported that DNA-dependent activator of IFN regulatory factors (DAI), also referred to as DLM-1/ZBP1, functions as a DNA sensor that activates the innate immune system. In the present study, we examined the regulation of the complex DNA-sensing system by DAI and othe...

OBJECTIVES Patient compliance influences results of treatment of mental disorders. The study compares four measures of treatment adherence. METHODS 103 subjects were examined in the early remission from an acute psychotic (schizophrenic or schizoaffective) crisis. Compared was patient's compliance assessed by two simple scales: 5-point POP (patient's self-rating) and 7-point POK (clinician's ...

Evaluating diffuse axonal injury (DAI) remains challenging in clinical sciences since the physiopathologic mechanism of DAI is still unclear. The calcium overload in the axoplasm is considered to be crucial for secondary axonal injury. The present study use calcium channel blocker, nimodipine, to explore the influence of Ca2+ in the pathogenesis of rat DAI. In the DAI group, the expressions of ...

Providing the appropriate access means for data mining services in Grid Environment is principal for combination of Grid and data mining. The transition from centralized data mining process as they are in traditional tools to Grid-compliant and Grid-based data mining services that can coordinate with each other is important to extract useful and potential knowledge/patterns from distributed dat...

Nilaparvata lugens (Stål) is a typical vascular feeder, primarily sucking the phloem sap of host plants. Its feeding on rice, Oryza sativa L., plants changes the pattern of allocation of assimilates between roots and shoots, and the root:shoot (R/S) ratio of assimilates is often measured as an index of physiological responses to N. lugens. The current study investigated changes in the R/S ratio...

Adhesive small bowel obstruction (ASBO) is an adverse consequence of abdominal surgery. Although the Kampo medicine Dai-kenchu-to is widely used in Japan for treatment of postoperative ASBO, rigorous clinical studies for its use have not been performed. In the present retrospective observational study using the Japanese diagnosis procedure combination inpatient database, we selected 288 propens...

DAI is a leading cause of the patient's death or lasting vegetable state following severe TBI, and up to now the detailed mechanism of axonal injury after head trauma is still unclear. Inflammatory responses have been proved to be an important mechanism of neural injury after TBI. However, most of these studies are concerned with focal cerebral injury following head trauma. In contrast to focal...

The aim of this study was to investigate the relationship between Turkish university students' awareness of malocclusion, their satisfaction with their personal dental appearance, and the severity of their occlusal irregularities. The sample consisted of 841 randomly selected university students, 522 (62.1 per cent) males and 319 (37.9 per cent) females, aged 17-26 years (mean age, 21.91+/-1.92...

journal.publications.chestnet.org of lesions associated with TBI is compounded by the Marshall clas sifi cation of head injury based on CT scanning. 2 These conditions cause coma when they affect brain perfusion and cortical or brain stem activity. DAI is only one possible physiopathologic mechanism causing coma after TBI and typically occurs during high-speed impact trauma causing rotational a...