Abstract To evaluate the hypothesis that offspring born to restricted- and over-fed ewes would exhibit decreased glucose tolerance, total cholesterol (TC), triglyceride (TG), increased leptin, multiparous Dorset (n = 46) pregnant with twins were fed 100%, 60% or 140% of National Research Council (NRC) requirements from d30±0.02 gestation until parturition. Offspring are referred as CON (n=10 ew...

Aggregation without the Aggravation? Nonparametric Analysis of the Representative Consumer In the tradition of Afriat (1967), Diewert (1973) and Varian (1982), we provide a revealed preference characterisation of the representative consumer. Our results are simple and complement those of Gorman (1953, 1961), Samuelson (1956) and others. They can also be applied to data very readily and without ...

We study a problem of repeated moral hazard where the e¤ect of e¤ort is persistent over time: each period’s outcome distribution is a function of a distributed lag of past e¤orts. We show that when the utility of the agent is linear in e¤ort, a simple rearrangement of terms in his lifetime utility translates this problem into a standard repeated moral hazard. As a consequence, the optimal consu...

This paper analyzes the effects of moral hazard on long-run consumption or utility. Given exponential utility, it is shown that the utility of those with unobservable endowments becomes arbitrarily negative as long as any positive fraction of otherwise identical agents have observable endowments. Next, it is shown that assuming a finite number of agents results in essentially the same outcomes ...

Complement-dependent cytotoxicity in tumor bearer sera (TBS) from Wistar rats carrying any of five transplantable aminoazo dye-induced hepatomas (D23, D33, D23/Not, D30, or D202) were investigated by a short-term 51Cr release assay. Extensive tests of various TBS against the hepatomas revealed that the tumors could be divided into two groups. Group 1 hepatomas (D23, D33, and D23/Not) all shared...

OBJECTIVE To evaluate the feasibility, safety, and efficacy of a novel Cocoon Duct Occluder device for the transcatheter closure (TCC) of large patent ductus arteriosus (PDA). METHODS In this prospective, non-randomized study, consecutive patients with large PDA (narrowest diameter: ≥3.5/4.0 mm in symptomatic/asymptomatic patients, respectively), who underwent TCC with Cocoon Duct Occluder at...

Carbamazepine belongs to the class II biopharmaceutical classification system (BCS) which is characterized by a high per-oral dose, a low aqueous solubility and a high membrane permeability. The bioavailability of such a drug is limited by the dissolution rate. In order to increase the drug dissolution, its solid dispersions were prepared by the cogrinding technique using an insoluble but highl...

Carbamazepine belongs to the class II biopharmaceutical classification system (BCS) which is characterized by a high per-oral dose, a low aqueous solubility and a high membrane permeability. The bioavailability of such a drug is limited by the dissolution rate. In order to increase the drug dissolution, its solid dispersions were prepared by the cogrinding technique using an insoluble but highl...

BACKGROUND Pulpa dentis D30 (PD: dental pulp of the calf, prepared in a homeopathic D30 potency) has been used in acute reversible pulpitis for pain relief and to avoid or postpone invasive dental treatment. PRIMARY STUDY OBJECTIVE To study short-term clinical outcomes of PD therapy for acute reversible pulpitis in routine dental practice. METHODS/DESIGN Prospective, observational, open-lab...