Although several cases of signet-ring cell carcinoma (SRCC) in the colorectum have been reported [1,2], there have been no reports of SRCC in the anus. The case presented here is the first reported case of primary pure SRCC of the anus. A 49-year-old man presented with anal bleeding. Colon endoscopy revealed a polyp in the anus, and polypectomy was performed The polypectomy specimen showed pure...

background: gastric and colorectal adenocarcinoma are the second and the fifth most common cancers in iran, respectively. expression of cytokeratin 7 (ck7) is established in most malignancies including gastric and colorectal adenocarcinoma. demonstration of ck7 could be related to prognostic factors and help to the better management of the patients. the objective of our study was to evaluate th...

Mucinous cystadenoma of the testis is a very rare tumor. Herein, we report a case of mucinous cystadenoma arising in the testis of a 61-year-old man, along with a literature review. Computed tomography showed a 2.5-cm-sized poorly enhancing cystic mass. Grossly, the tumor was a unilocular cystic mass filled with mucinous material and confined to the testicular parenchyma. Histologically, the cy...

In the present study we investigated the cytokeratin (CK) polypeptide expression in gastric and colonic adenocarcinomas. A battery of monoclonal anti-cytokeratin-specific antibodies and anti-vimentin were used. While the majority of cases displayed simple epithelial characteristics, in three of 17 cases of gastric adenocarcinomas and in one of 20 cases of colonic adenocarcinomas, CK polypeptide...

background and objective: nasal polyp is the most common benign mass of the nasal cavity and it is originated from nasal cavity or sinuses. cytokeratins (ck) are intermediate filament proteins that provide mechanical support in epithelial cells. the purpose of this study was to compare the expression of cytokeratin 7 in epithelium of nasal polyps and nasal mucosa in chronic rhinosinusitis. mate...

Low-grade adenocarcinomas that primarily arise within the sinonasal tract are uncommon tumors. We report here on three cases of primary sinonasal low-grade adenocarcinomas. The patients were 2 females and 1 male with ages of 48, 57 and 64, respectively. Microscopically, the tumors had a well developed tubulopapillary growth pattern that consisted of columnar or pseudostratified cells with eosin...

OBJECTIVE Ovarian mucinous metastases commonly present as the first sign of the disease and are capable of simulating primary tumors. Our aim was to investigate the role of intratumoral lymphatic vascular density together with other surgical-pathological features in distinguishing primary from secondary mucinous ovarian tumors. METHODS A total of 124 cases of mucinous tumors in the ovary (63 ...

The keratins, members of the intermediate filament family, are characteristically expressed in epithelial cells. In the various types of epithelia, the keratin expression pattern is characterized by cell-type specific combinations of the keratin isotypes with a plain pattern in monolayered (simple) epithelia and more complex patterns in stratified and pseudostratified epithelia. Here we demonst...

AIMS To investigate differences in expression of keratin 20, a cytoskeletal protein in gastrointestinal epithelial cells, in completely differentiated intestinal metaplasia (type I) and incomplete metaplasia (types II and III). METHODS Gastric biopsy specimens from 66 patients with intestinal metaplasia were analysed immunohistochemically. Expression of keratin 20 was quantified as the percen...