نتایج جستجو برای: cystatin c

تعداد نتایج: 1057234  

2011
Yun Kyung Jeon Mi Ra Kim Jung Eun Huh Ji Young Mok Sang Heon Song Sang Soo Kim Bo Hyun Kim Soo Hyoung Lee Yong Ki Kim In Joo Kim

This study was done to evaluate clinical usefulness of cystatin C levels of serum and urine in predicting renal impairment in normoalbuminuric patients with type 2 diabetes and to evaluate the association between albuminuria and serum/urine cystatin C. Type 2 diabetic patients (n = 332) with normoalbuminuria (n = 210), microalbuminuria (n = 83) and macroalbuminuria (n = 42) were enrolled. Creat...

2017
Wei-Zhong Feng Jun-Qing Zhou Guang-Mao Yu Yong Zeng Peng Xu

Increased serum cystatin C levels are related to the prognosis of cardiovascular diseases. This study aims to investigate the effect of admission serum cystatin C levels on short- and long-term mortality in patients with acute type A aortic dissection (ATAAD). From 2010 to 2014, 136 consecutive patients with ATAAD were enrolled and followed up. Clinical data and laboratory assays including were...

2015
Ying Shen Feng Hua Ding Rui Yan Zhang Qi Zhang Lin Lu Wei Feng Shen Stephan Henrik Schirmer

OBJECTIVE We investigated whether and to what extent cystatin C was associated with angiographic coronary collateralization in patients with stable coronary artery disease and chronic total occlusion. METHODS Serum levels of cystatin C and high-sensitive C-reactive protein (hsCRP) and glomerular filtration rate (GFR) were determined in 866 patients with stable angina and angiographic total oc...

2013
Xin Li Hang Zhu Peng Li Qian Xin Jie Liu Wei Zhang You-Hong Xing Hao Xue

BACKGROUND Serum cystatin C levels can be used to predict morbidity and mortality in patients with cardiovascular disease. However, the clinical relevance of serum cystatin C levels in patients with hypertensive left ventricular hypertrophy (LVH) has rarely been investigated. We designed the present study to investigate whether serum cystatin C levels are associated with cardiac structural and ...

Journal: :Scandinavian journal of clinical and laboratory investigation 2009
Pierre Delanaye Etienne Cavalier Annie Saint-Remy Laurence Lutteri Jean-Marie Krzesinski

BACKGROUND The prevalence of stage 3 chronic kidney disease (CKD) is increasing, calculated using the modification of diet in renal disease (MDRD) study equation for estimating glomerular filtration rate (GFR). Cystatin C-based equations are also being used to estimate GFR. Using creatinine-based and cystatin C-based equations, the aim of our study was to measure the difference in prevalence of...

Journal: :Circulation journal : official journal of the Japanese Circulation Society 2013
Toshihiko Yamamoto Masayuki Shimano Yasuya Inden Shinjiro Miyata Yoko Inoue Naoki Yoshida Yukiomi Tsuji Makoto Hirai Toyoaki Murohara

BACKGROUND Cardiac resynchronization therapy (CRT) has been reported to improve symptoms and cardiac performance in patients with severe heart failure (HF), but CRT recipients with advanced HF do not always experience improved mortality rates. Cystatin C has recently been involved in HF, but the association of serum cystatin C level with adverse events and long-term prognosis after CRT is unkno...

2010
Joanna Pollak Aneta Szymanska Veronica Lindstrom Anders Grubb

Cystatin C is produced in all nucleated cells. It has various functions and biological activities. Researchers are focused on its role in kidney diseases as a marker of glomerular filtration but also as a very important link in development of amyloid diseases. This work describes expression and purification of both wild type (wt) and stabilized form (stab 1 and 2) of wt cystatin C and amyloid-f...

2014
Wai H. Lim Joshua R. Lewis Germaine Wong Robin M. Turner Ee M. Lim Peter L. Thompson Richard L. Prince Antonio Carlos Seguro

BACKGROUND Reduced estimated glomerular filtration rate (eGFR) using the cystatin-C derived equations might be a better predictor of cardiovascular disease (CVD) mortality compared with the creatinine-derived equations, but this association remains unclear in elderly individuals. AIM The aims of this study were to compare the predictive values of the Chronic Kidney Disease Epidemiology Collab...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2004
Per Eriksson Hiroyuki Deguchi Ann Samnegård Pia Lundman Susanna Boquist Per Tornvall Carl-Göran Ericsson Lott Bergstrand Lars-Olof Hansson Shu Ye Anders Hamsten

OBJECTIVE Overexpression of elastolytic cysteine and aspartic proteases, known as cathepsins, is implicated in atherogenesis. The potential significance of imbalance in expression between cathepsins and their inhibitor cystatin C in cardiovascular disease has been highlighted by the demonstration of cystatin C deficiency in human atherosclerosis and abdominal aortic aneurysms. METHODS AND RES...

Journal: :Annales de biologie clinique 2009
Nevio Taglieri Wolfgang Koenig Juan Carlos Kaski

Patients with chronic kidney disease (CKD) are at high risk for developing cardiovascular disease (CVD) and cardiovascular events. Cystatin C, a protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect small reductions in glomerular filtration rate. This report presents a review of...

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