This Application Note demonstrates the capability of the Agilent 1290 Infi nity 2D-LC Solution for heart-cutting applications. As an example, a minor impurity is resolved by heart cutting from a co-eluting main compound. The minor impurity, which is isolated on a second-dimension column after heart cutting, is verifi ed by additional spiking and statistical evaluation of the separation performa...

Developments in machine tools tend towards high speed technology, including high-speed machining (HSM) and high-speed cutting (HSC), especially in high speed end milling applications [1] and [2]. High speed technology applications in machine tools are characterised by a high feeding speed, low axial and radial cutting depth, increased metal removal rate, simplified processing, and reduced costs...

High-speed steel (HSS) tools are the most commonly used tools in small and medium-scale industry. Cryogenic treatment can be used to enhance the tool life. Studies on cryogenically treated (CT) cutting tools show micro structural changes in the material that can influence the life of the tools significantly. This paper primarily reports performance of CT HSS tools as compared to untreated (UT) ...

In this study, we aim to develop a narrow-diameter and long-bore device for minimally invasive surgery that achieves the simultaneous cutting and suction of body tissue such as the diseased part of an organ. In this paper, we propose a screw made of a thin metal plate, and we developed a prototype device using this screw. For smooth operation, the suction performance must be superior to the cut...

The different player positions in rugby union may place varying demands on a reconstructed anterior cruciate ligament (ACL) in regards to 'cutting manoeuvres', this in turn may effect performance. In order to investigate sporting performance post reconstruction, a questionnaire was sent to amateur rugby clubs affiliated to the Oxfordshire Rugby Football Union (R.F.U). From the returned question...

There are many non-linear interaction factors responsible for the performance of the laser cutting process. Identification of the dominant factors that significantly affect the cut quality is important. In recent years the researchers have explored the number of ways to improve the quality of cutting in the different lasers. This paper reviews the research work carried out so far in the area of...

The analysis of drill cutting angles is important for the design of high-performance drill geometry. The cutting angles along the cutting edge of a drill are determined by the combination of its flute and flank surfaces. This paper examines the analysis of both flute and flank surface models and the evaluation of drill cutting angles. A new mathematical model for an arbitrary drill flute face i...

Abrasive waterjet cutting is one of the nontraditional machining processes capable of cutting wide range of hard-to-cut materials. This process incurs relatively higher initial investment, maintenance and operating costs. Therefore optimum choice of the process parameters is essential for the economic, efficient and effective utilization of this process. This paper assesses the influence of pro...

The aim of this paper is to investigate the effect of cutting speed and uncut chip thickness on cutting performance. A Finite Element Method (FEM) based on the ABAQUS explicit software which involves Johnson-Cook material mode and Coulombs friction law was used to simulate of High Speed Machining (HSM) of AISI 1045 steel. In this simulation work, feed rate ranging from 0.05 mm/rev to 0.13 mm/re...

IT performance measurement is often associated by chief executive officers with IT cost cutting although IT protects business processes from increasing IT costs. IT cost cutting only endangers the company’s efficiency. This opinion discriminates those who do IT performance measurement in companies as a bean-counter. The present paper describes an integrated reference model for IT performance me...