U6 small nuclear RNA (snRNA) is a required component in the splicing of eukaryotic pre-mRNAs. Mammalian U6 snRNA was synthesized in vitro by T7 RNA polymerase and purified on polyacrylamide gels. This U6 RNA, with pppG on its 5' end, was accurately capped to CH3-O-pppG, when incubated with HeLa cell extract and this capping was dependent on the capping signal present within the U6 snRNA. When g...

We define generalized Mellin transforms of mixed cusp forms, show its convergence, and prove that the function obtained by such a Mellin transform of a mixed cusp form satisfies a certain functional equation. We also prove that a mixed cusp form can be identified with a holomorphic form of the highest degree on an elliptic variety.

It is currently unclear whether the T cell dysfunctions observed during active systemic lupus erythematosus (SLE) reflect a disorder intrinsic to the T cell or defects that result from interaction with anti-T cell autoantibody. To determine whether a disorder intrinsic to the T cell exists in SLE, the T cell capping mechanism was selected as a model of cellular function. The normal T cell cappi...

Actin-capping and anti-capping proteins are crucial regulators of actin dynamics. Recent studies have indicated that these proteins may be heavily involved in all stages of synaptogenesis, from the emergence of filopodia, through neuritogenesis and synaptic contact stabilization, to the structural changes occurring at the synapse during potentiation phenomena. In this review, we focus on recent...

Because biogas bubbles can influence cap integrity, the effect of capping and cap material on the ebullition potential in sediments must be studied. The goal of this comprehensive study was to determine the short-term effect of capping regime on the activity, metabolic potential, and community structure of sediment microorganisms. To evaluate the effect of capping (sand, synthetic aggregate, an...

Talon cusp is a rare developmental anomaly that occurs most commonly on the lingual side of the incisors. It may cause various clinical problems, such as occlusal interference, irritation of the tongue, pulpal necrosis, caries and periodontal problems. Genetics is thought to be a major cause for the occurrence of this anomaly. This article reports three cases of talon cusp in three members of t...

The quotient-cusp singularities are isolated complex surface singularities that are double-covered by cusp singularities. We show that the universal abelian cover of such a singularity, branched only at the singular point, is a complete intersection cusp singularity of embedding dimension 4. This supports a general conjecture that we make about the universal abelian cover of a Q-Gorenstein sing...

Talon cusp is a common dental anomaly affecting maxillary central incisors. Gradual grinding of this additional cusp is commonly followed now. Advocated below is a new technique explaining the use of air abrasion and putty index during the stepwise reduction of the cusp. The technique is advantageous in preventing patient discomfort and tracking the amount of reduction in a predictable way.