in this paper, we give some characterizations for legendre spherical, legendre normal and legendre rectifying curves in the 3-dimensional sasakian space. furthermore, we show that legendre spherical curves are also legendre normal curves. in particular, we prove that the inverse of curvature of a legendre rectifying curve is a non-constant linear function of the arclength parameter.

a convenient liquid chromatographic-single quadrupole mass spectrometric (lc-ms) method was developed and validated for dexchlorpheniramine maleate (inn name: chlorphenamine) determination in human plasma. the need for just a single liquid-liquid extraction with ethyl acetate and being highly sensitive were the advantages of this method. the linearity was also excellent over the range of 1 to 1...

BACKGROUND AND THE PURPOSE OF THE STUDY As a novel drug in the treatment of cardiac diseases, dl-praeruptorin A (Pd-Ia) is the major active component of traditional herbal medicine Peucedanum praeruptorum Dunn and is metabolized primarily via cytochrome P450 isozymes (CYP) 3A1 and 3A2 in rats. In the present study, the influence of liver cirrhosis on pharmacokinetics of Pd-Ia and hepatic mRNA e...

OBJECTIVE The objective of our study was to determine reference intervals and biologic variation for testosterone (T), free testosterone (fT), and free androgen index (FAI) in women with accurate methods and to test the discriminative value of these parameters in a polycystic ovary syndrome (PCOS)-population. METHODS Serum was obtained daily during a normal menstrual cycle from 25 healthy wom...

background methotrexate is a folic acid antagonist that has been in clinical use for five decades. its use in patients with brain tumors is primarily confined to primary central nervous system lymphoma (pcnsl), in which it is the cornerstone of chemotherapy. objectives a selective and sensitive high-performance liquid chromatography-electrospray ionization-mass spectrometry method was developed...

We propose a single cell gap vertical-alignment transflective LCD with patterned electrodes using a positive dielectric anisotropic liquid crystal. As compared to prior attempts using a positive LC in VA configurations, our new design significantly reduces the threshold and on-state voltages to a range reachable by portable electronic displays. In addition, the light efficiency is also enhanced...

Abstract Background After Gagner introduced laparoscopic liver resection (LLR) in 1992, it was not until 2004 that the first series with more than ten major resections reported. Furthermore, a multicentre study by Allard et al., 2015 revealed laparoscopy only used 176 (6.7%) patients out of total 2620 treated for colorectal metastasis (CRLM). This lag time establishment LLR attributed to steep ...

since its introduction in 1988, laparoscopic cholecystectomy (lc) has become the procedure of choice in the management of gallstone disease. it has well established advantages compared to its traditional open counterpart such as reduction in hospital stay and related costs, more rapid return to work, and reduction in pain and cosmetic problems. lc, like any other procedure, has its own indicati...

BACKGROUND Accurate localisation of the lumpectomy cavity (LC) volume is one of the most critical points in 3D-conformal Partial breast irradiation (3D-APBI) treatment planning because the irradiated volume is restricted to a small breast volume. Here, we studied the role of the placement of surgical clips at the 4 cardinal points of the lumpectomy cavity in target delineation. METHODS Forty ...

Single-incision laparoscopic surgery is cosmetically beneficial, but technically challenging. In this study, the learning curve (LC) for single-incision laparoscopic right hemicolectomy (SILRC), incorporating complete mesocolic excision to resect right-sided colon cancer, was investigated through multidimensional techniques. Between December 2009 and May 2015, 64 patients each underwent SILRC o...