− P-gp plays a critical role in drug disposition and represents a mechanism for the development of multidrug resistance. Flavonoids, a major class of natural compounds widely present in foods and herbal products, have been shown to inhibit P-gp. Therefore, the aim of this study was to identify new candidate chemosensitizers by screening various plant extracts. The ability of natural plant extra...

Pterygium is a relatively common eye disease that can display an aggressive clinical behaviour. To evaluate the in vitro effects of Curcuma longa on human pterygium-derived keratinocytes, specimens of pterygium from 20 patients undergoing pterygium surgical excision were collected. Pterygium explants were put into culture and derived keratinocytes were treated with an alcoholic extract of 1.3% ...

Choleretic drugs are used in some conditions e.g., fat maldigestion. Verapamil is a calcium channel blocker, which inhibits p-glycoprotein (P-gp) and may affect bile accumulation. Curcuma longa is traditionally used for treatment of maldigestion and as food additive. In this study, the effect of verapamil and Curcuma longa was compared on bile accumulation in gall bladder of mice. This simple a...

This paper deals with the ethnobotany of turmeric (Curcuma longa L.) an ancient crop having its origin and early domestication in South Asia and ethnobotanically very important. Due to its manifold uses in cultural and social life of ethnic people of Asia with special reference to South and South East Asia, has very early domestication and evolutionary history. In India, its history begins from...

BACKGROUND Curcuma extract exerts a myorelaxant effect on the mouse intestine. In view of a possible use of curcuma extract in motor functional disorders of the gastrointestinal tract, a safety profile study has been carried out in the mouse. METHODS Thirty mice were used to study the in vitro effect of curcuma on gallbladder, bladder, aorta and trachea smooth muscular layers and hearth inotr...

Curcuma oligantha Trimen var. oligantha (Zingiberaceae) is an erect perennial herb with white flowers spotted yellow at the throat of the labellum. It is distributed in Sri Lanka and Karnataka (1, 2). The Curcuma rhizomes are large, tuberous, orangered and aromatic and substituted for turmeric. The rhizomes are prescribed to treat bruises, sprains, skin eruptions, infections and to improve comp...

Background The objective of the present study was to determine the optimum dosage of probiotic in the diet of keureling fish ( Tor tambra) fry. MethodsLactobacillus casei from Yakult® was used as a starter, and enhanced with Curcuma xanthorrhiza, Kaempferia galanga and molasses. The mixture was fermented for 7 days prior to use as probiotic in a formulated diet containing 30% crude protein. Fou...

background and aims: one of the most common chronic diseases in the world is tooth decay. a variety of bacteria are involved in this disorder of which streptococcus mutants is the most common. essential oils are considered as new natural compounds for use in combating drug-resistant bacteria. this study was aimed to evaluate the antibacterial activity of some essential oils prepared from eucaly...

Background: Obesity and increased body mass index (BMI) affect the reproductive parameters in men such as poor semen quality, decreased sperm concentration, decreased normal-motile sperm cells and increased DNA fragmentation index. Lipid peroxidation contributes to the damage of the sperm plasma membrane. The Curcuma Longa is a resource of antioxidants, hence in this study also was evaluated th...