نتایج جستجو برای: cupper metalloenzymes

تعداد نتایج: 752  

2016
Yajie Wang Huimin Zhao Jose M. Palomo

The application of biocatalysts in the synthesis of fine chemicals and medicinal compounds has grown significantly in recent years. Particularly, there is a growing interest in the development of one-pot tandem catalytic systems combining the reactivity of a chemical catalyst with the selectivity engendered by the active site of an enzyme. Such tandem catalytic systems can achieve levels of che...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2012
Ricardo Bermejo-Deval Rajeev S Assary Eranda Nikolla Manuel Moliner Yuriy Román-Leshkov Son-Jong Hwang Arna Palsdottir Dorothy Silverman Raul F Lobo Larry A Curtiss Mark E Davis

Isomerization of sugars is used in a variety of industrially relevant processes and in glycolysis. Here, we show that hydrophobic zeolite beta with framework tin or titanium Lewis acid centers isomerizes sugars, e.g., glucose, via reaction pathways that are analogous to those of metalloenzymes. Specifically, experimental and theoretical investigations reveal that glucose partitions into the zeo...

2017
Ruijie K. Zhang David K. Romney S. B. Jennifer Kan Frances H. Arnold

Directed evolution is a powerful algorithm for engineering proteins to have novel and useful properties. However, we do not yet fully understand the characteristics of an evolvable system. In this chapter, we present examples where directed evolution has been used to enhance the performance of metalloenzymes, focusing first on ‘classical’ cases such as improving enzyme stability or expanding th...

2017
Amanda G Jarvis Lorenz Obrecht Peter J Deuss Wouter Laan Emma K Gibson Peter P Wells Paul C J Kamer

Artificial metalloenzymes (ArMs) are hybrid catalysts that offer a unique opportunity to combine the superior performance of natural protein structures with the unnatural reactivity of transition-metal catalytic centers. Therefore, they provide the prospect of highly selective and active catalytic chemical conversions for which natural enzymes are unavailable. Herein, we show how by rationally ...

Journal: :Indonesian Journal of Electrical Engineering and Informatics 2021

Partial discharges occur the biggest failure problem in power cable insulation due to distortion of electrical stress. In this paper, it has been investigated on effect spherical nanoparticles Barium titanate (BaTiO 3) and Clay for enhancing electrostatic field distribution single three-core cables. It applied new strategies nanotechnology techniques designing innovative polyvinyl chloride mate...

Journal: :Proceedings of the Japan Academy, Series B 2020

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