PURPOSE Computed tomographic colonography (CTC) is a new noninvasive technology proposed as an option for colorectal cancer screening. The purpose of this study was to identify the percentage of US hospitals that offered CTC between 2005 and 2008 and factors that motivated or impeded adoption. METHODS Data on the provision of colorectal cancer screening services by nonfederal, general hospita...

BACKGROUND The purpose of this study was to evaluate the association of circulating tumour cell (CTC) counts, before and after commencing treatment, with overall survival (OS) in patients with castration-resistant prostate cancer (CRPC). EXPERIMENTAL DESIGN A 7.5 ml of blood was collected before and after treatment in 119 patients with CRPC. CTCs were enumerated using the CellSearchSystem. ...

Metastatic colorectal cancer (mCRC) relies on the detachment of aggressive malignant cells from the primary tumor into the bloodstream and, concordantly, the presence of these Circulating Tumor Cells (CTC) is associated with a poor prognosis. In this work, the molecular characterization of CTC from mCRC patients was approached, with the aim of understanding their biology and improving their cli...

As the prognosis of colorectal cancer (CRC) patients is mostly determined by the occurrence of distant metastases, circulating tumor cells (CTC) may be an attractive therapeutic target. Despite the rarity of CRCderived CTC, considerable progress has recently been made in the investigation of their molecular characteristics. In this review article we present recent clinical and molecular data on...

three hundred eighteen young holstein bulls (initial bw = 375 ± 17.5 kg) were randomly allotted to one of six treatments in a completely randomized design for 56 d the treatments of which consisted of 1) the basal diet (control); 2) basal diet plus 30 mg of cu/kg of dm as cuso4; 3) basal diet plus 150 mg of zn/kg of dm as znso4; 4) basal diet plus chlortetracycline (200 mg/animal/d; ctc); 5) ba...

OBJECTIVE In case of incomplete colonoscopy, several radiologic methods have traditionally been used, but more recently, capsule endoscopy was also shown to be accurate. Aim of this study was to compare colon capsule endoscopy (CCE) and CT colonography (CTC) in a prospective cohort of patients with incomplete colonoscopy. DESIGN Consecutive patients with a previous incomplete colonoscopy unde...

OBJECTIVE The purpose of this study was to evaluate the effectiveness of CT colonography (CTC) as a triage technique in faecal occult blood test (FOBT)-positive screening participants. METHODS Consecutive guaiac (G-FOBT) and immunochemical (I-FOBT) FOBT-positive patients scheduled for colonoscopy underwent CTC with iodine tagging bowel preparation. Each CTC was read independently by two exper...

PURPOSE Due to their minimal-invasive yet potentially current character circulating tumor cells (CTC) might be useful as a "liquid biopsy" in solid tumors. However, successful application in metastatic renal cell carcinoma (mRCC) has been very limited so far. High plasticity and heterogeneity of CTC morphology challenges currently available enrichment and detection techniques with EpCAM as the ...

BACKGROUND This study estimated the cost effectiveness of community-based therapeutic care (CTC) for children with severe acute malnutrition (SAM) in Sidama Zone, Ethiopia compared to facility based therapeutic feeding center (TFC). METHODS A cost effectiveness analysis comparing costs and outcomes of two treatment programmes was conducted. The societal perspective, which considers costs to a...

Purpose: Presence of circulating tumor cells (CTC) in metastatic carcinoma is associated with poor survival. Phenotyping and genotyping of CTC may permit "real-time" treatment decisions, provided CTCs are available for examination. Here, we investigate what is needed to detect CTC in all patients. Experimental Design: CTCs enumerated in 7.5 mL of blood together with survival from 836 patients w...