Spinal-induced hypotension remains the most common complication associated with spinal anesthesia for cesarean delivery. Recent evidence indicates that a 20-mL/kg bolus via pressurized infusion system administered at the time of subarachnoid block (SAB) (coload) may provide better prophylaxis than the traditional administration of a 20-mL/kg crystalloid infusion (preload) approximately 20 minut...

BACKGROUND Quantification of renal fluid conservation is possible by urine analysis, and the results can indicate dehydration. The present report sought to determine whether this fluid retention correlates with fluid requirements during major abdominal surgeries that have estimated operating times ≥ 2 h. METHODS Urine colour, specific weight, osmolality and creatinine concentration were used ...

UNLABELLED We evaluated in this qualitative systematic review the efficacy of increasing central blood volume on the incidence of hypotension after spinal anesthesia for elective cesarean delivery. Randomized controlled trials investigating any method of increasing central blood volume before the initiation of obstetric spinal anesthesia were sought by using MEDLINE (1966-2000), Embase (January...

When rat liver microsomal aldehyde dehydrogenase (msALDH) was overexpressed in COS-1 cells by cDNA transfection, large granular structures containing both msALDH and endogenous protein disulfide isomerase appeared (Masaki et al. (1994) J. Cell Biol. 126, 1407-1420). Confocal laser microscopy revealed that these granular structures are dispersed throughout the cytoplasm. Electron microscopy show...

Giant granules ( 1 sm in diameter), Auer rods, and unique giant granules that contained crystalloid material were investigated in monoblasts from a patient with acute monocytic leukemia using ultrastructural and cytochemical techniques. The latter granule type differed from abnormal granules previously described in leukocytes. In Wright’s stained preparations, these granules appeared to be crys...

BACKGROUND Damage control resuscitation recommends use of more plasma and less crystalloid as initial resuscitation in treating hemorrhage. The purpose of this study was to evaluate resuscitation with either blood components or conventional fluids on coagulation and blood loss. STUDY DESIGN AND METHODS Isofluorane-anesthetized, instrumented pigs (eight per group) underwent controlled hemorrha...

BACKGROUND Prior studies in critically ill patients suggest the supra-physiologic chloride concentration of 0.9% ("normal") saline may be associated with higher risk of renal failure and death compared to physiologically balanced crystalloids. However, the comparative effects of 0.9% saline and balanced fluids are largely unexamined among patients outside the intensive care unit, who represent ...

introduction: the administration of crystalloid fluids is considered as the first line treatment in management of trauma patients. infusion of intravenous fluids leads to various changes in hemodynamic, metabolic and coagulation profiles of these patients. the present study attempted to survey some of these changes in patients with mild severity trauma following normal saline infusion. methods:...