BACKGROUND Cryotherapy is a safe, affordable, and effective method of treatment for cervical intraepithelial neoplasia. In some low-resource settings, environmental conditions or qualities of the refrigerant gas can lead to blockage of cryotherapy equipment, terminating treatment. A prototype of a gas conditioner to prevent operational failure was designed, built, and field tested. METHODS Th...

We analyzed the management and risk of subsequent cervical intraepithelial neoplasm 3 (CIN3) and invasive cervical cancer in women with low-grade squamous intraepithelial lesion (LSIL) cytology. A total of 53,293 women with a new diagnosis of cytologic LSIL were identified in Taiwan's national cervical screening registration database. Based on the retrieved clinical management data, the inciden...

Pentavalent antimonials, as the 1st choice for the treatment of cutaneous leishmaniasis (CL), have various side effects. Also, there are some reports of drug resistance. Due to its safety, cryotherapy can be a good alternative or complementary treatment in CL. The aim of this study was to explore the possible systemic immunological mechanisms of cryotherapy besides its local effects in the trea...

BACKGROUND A cooling system based on polyurethane preshaped masks for postoperative cryotherapy, named Hilotherm, has been recently introduced. The purpose of this study was to evaluate the effectiveness of this equipment in controlling postoperative edema and compare the results with those obtained with a group treated with conventional cryotherapy and a group not treated with cryotherapy. M...

STUDY DESIGN Historical controlled trial. PURPOSE To clarify the usefulness of cryotherapy after spine surgery. OVERVIEW OF LITERATURE Cryotherapy has generally been performed subsequent to surgery on joints and in this application its clinical effects are well understood. However, cryotherapy has yet to be used following spine surgery. Its clinical efficacy in this context is unknown. ME...

PURPOSE The objective of this investigation was to determine the effect of continuous cryotherapy on glenohumeral joint and subacromial space temperatures in the postoperative shoulder. TYPE OF STUDY Prospective, randomized, and controlled clinical trial. METHODS Twenty patients (10 cryotherapy, 10 controls) with a full-thickness rotator cuff repair were monitored with temperature sensors i...

PURPOSE To compare the long-term outcomes of peripheral retinal cryoablation to conventional treatment for active pars planitis. DESIGN Retrospective, interventional, comparative case series. METHODS Review at a single institution was conducted to compare the effect of cryotherapy to eyes with pars planitis to those receiving conventional therapy (topical, regionally injected, or oral corti...

BACKGROUND Warts are common and induce physical and emotional discomfort. Numerous therapies exist, yet none is optimal. Despite theoretical advantages, immunotherapeutic modalities are often neglected as first-line wart therapies. OBJECTIVE To compare treatment with intralesional skin test antigen injection of 1 wart vs cryotherapy of all warts. DESIGN Pilot study. SETTING University der...

AIM To determine the frequency of cervical cytologic abnormalities in patients who were diagnosed as having CIN 1 and had undergone either cryotherapy or expectant management. METHODS A retrospective medical record review of 87 patients with colposcopic cervical biopsy-proven CIN 1, was undertaken including age, parity, menstruation status, cervical cytology reports, colposcopic findings, and...

CONTEXT Application of cryotherapy modalities is common after acute shoulder injury and as part of rehabilitation. During athletic events, athletes may return to play after this treatment. The effects of cryotherapy on dominant shoulder proprioception have been assessed, yet the effects on throwing performance are unknown. OBJECTIVE To determine the effects of a cryotherapy application on sho...