normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: to determine the prevalence of cryoglobulins in iranian patients with systemic lupus erythematosus (sle) and evaluate the correlation of cryoglobulins with disease activity in these patients. materials and methods: in a cross-sectional study, we investigated 80 consecutive women who fulfilled the 1982 revised c...

INTRODUCTION Laboratory tests play a central role in assessing a patient and orienting the diagnostic evaluation. We report a case where the discrepancy between the manual and automatic cell count gave a hint to the final diagnosis. CASE PRESENTATION A 55-year-old Caucasian man, known to have hepatitis C, was admitted with acute respiratory failure secondary to acute pulmonary edema and diffu...

Cryoglobulinemia is characterized by a wide range of causes, symptoms, and outcomes. Hepatitis C virus (HCV) infection is detected in 30%Y100% of patients with cryoglobulins. Although more than half the patients with cryoglobulinemic vasculitis present a relatively benign clinical course, some may present with potentially lifethreatening situations. We conducted the current study to analyze the...

Hepatitis C virus (HCV) represents a major public health problem as a causative agent in developing chronic hepatitis, cirrhosis, and hepatocellular carcinoma. In recent years it has become known that HCV induces a broad spectrum of extrahepatic manifestations, including some cutaneous ones such as mixed cryoglobulinemia, porphyria cutanea tarda, leukocytoclastic vasculitis, lichen planus (LP),...

Introduction Cold-shock precipitating proteins - cryoglobulins damage various vessels and, depending on the localization of damages, may lead to functional disorders of various organs and body systems. Evidently, cryoglobulinemia may have a negative influence on the reproductive system's condition, thus, this process requires detailed study. Material and methods Clinical examples, indicating ...

Copyright © 2013 Massachusetts Medical Society. Cryoglobulins are immunoglobulins characterized by their insolubility at low temperatures and their dissolution after rewarming.1,2 On the basis of their immunochemical composition, cryoglobulins are classified as either single (type I), consisting of a monoclonal immunoglobulin, or mixed, comprising two or more immunoglobulin isotypes, with (type...