Recent descriptions of blood vessels recovered from dinosaur bones have raised many questions regarding tissue diagenesis and the associated chemical pathways that led to preservation. Previous analyses have identified preserved elastin and collagen proteins in a variety of specimens [1][2]. In particular, the mechanical, chemical, and thermal susceptibility of fibrillar collagen is partially d...

Microparticles composed of (meth)acrylic acid, potassium (meth)acrylate, and trifunctional pentaerythritol were prepared using a thermally initiated free radical precipitation polymerization in ethyl acetate. The particle synthesis method was investigated, and the structure and morphology of the microparticles was evaluated using Fourier transform infrared spectroscopy and scanning electron mic...

AIMS To provide common Organic Chemistry/Polymer Science thermoset free-radical crosslinking Sciences for Medical understanding and also present research findings for several common vitamins/antioxidants with a new class of drugs known as free-radical inhibitors. STUDY DESIGN Peroxide/Fenton transition-metal redox couples that generate free radicals were combined with unsaturated lipid oils t...

RNA-binding proteins (RBPs) are key players in post-transcriptional regulation of gene expression in eukaryotic cells. To be able to unbiasedly identify RBPs in Saccharomyces cerevisiae, we developed a yeast RNA interactome capture protocol which employs RNA labeling, covalent UV crosslinking of RNA and proteins at 365nm wavelength (photoactivatable-ribonucleoside-enhanced crosslinking, PAR-CL)...

Disulfide crosslinking of proteins is typically performed by treating proteins bearing cysteine residues with small-molecule disulfide reagents. The process results in the formation of a mixed disulfide intermediate, which then reacts with the cysteine residue of another protein molecule to form the crosslinked product. This second step requires the intimate association of two large reactants. ...

Enzymatic crosslinking of proteins is often limited by the steric availability of the target residues, as of tyrosyl side chains in the case of tyrosinase. Carrying an N-terminal peptide-tag containing two tyrosine residues, the fluorescent protein C-phycocyanin HisCPC from Synechocystis sp. PCC6803 was crosslinked to fluorescent high-molecular weight forms with tyrosinase. Crosslinking with ty...

he undergrounding of energy transmission cables is widely recognized as a good means to provide reliable supplies of power at a low total cost [1], [2]. As utilities increasingly acknowledge this and install many more high voltage (HV) and extra high voltage (EHV) cables, they will face a major challenge: namely, sourcing the increased amount of high quality power cable with the cable manufactu...