INTRODUCTION Slowly progressive cognitive decline is the most frequent initial manifestation in MM2-cortical-type sporadic Creutzfeldt-Jakob disease. Agraphia has never been noted in patients with this type of sporadic Creutzfeldt-Jakob disease, however, we report the case of a Japanese patient with sporadic Creutzfeldt-Jakob disease in whom agraphia of Kanji was an initial cardinal symptom. ...

1 Collinge J. Variant Creutzfeldt-Jakob disease. Lancet 1999;354:317-23. 2 Schreuder BEC, van Keulen LJM, Vromans MEW, Langeveld JPM, Smits MA. Preclinical test for prion diseases. Nature 1996;381:563. 3 Hill AF, Butterworth RJ, Joiner S, Jackson G, Rosser MN, Thomas DJ, et al. Investigation of variant Creutzfeldt-Jakob disease and other human prion disease with tonsil biopsy samples. Lancet 19...

Nation-wide surveillance of human transmissible spongiform encephalopathies (also known as prion diseases), the most common being Creutzfeldt-Jakob disease, is performed by the Australian National Creutzfeldt-Jakob Disease Registry, based at the University of Melbourne. Prospective surveillance has been undertaken since 1993 and over this dynamic period in transmissible spongiform encephalopath...

Introduction Although Creutzfeldt-Jakob disease (CJD) is rare, its rapid course, its infection control implications and the link between bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease (vCJD) make this disease relevant to all clinicians. The emergence of vCJD has prompted an explosion in the amount of research into the disorder, leading to new developments in both diagnos...

Since 1996 with the recognition of a variant form, Creutzfeldt-Jakob disease has become more prominent in the medical literature. Of particular interest to anaesthetists is the risk of iatrogenic spread of the disease. In this article, the relevant literature is reviewed and the experience within New Zealand examined. The presentation, pathology and incidence of the disease is reviewed and the ...

Human prion disease is known as new variant Creutzfeldt-Jakob disease (CJD), prion protein is not virus, but a special protein which is infectious (protinactious infectious particles, PRION). Creutzfeldt-Jakob disease is a group of infectious prion protein caused by sporadic, dominantly inherited, transmissible neurodegenerative disease, which is characterized by pathologic spongy degeneration ...

BACKGROUND Epidemiological studies on the potential role of surgery in Creutzfeldt-Jakob Disease transmission have disclosed associations with history of specific surgical interventions or reported negative results. METHODS Within the context of a case-control study designed to address surgical risk of sporadic Creutzfeldt-Jakob Disease in Nordic European countries (EUROSURGYCJD Project), a s...

It was found that Asthma, Chronic Obstructive Pulmonary Disease, Diabetes, Hepatitis C and HIV / AIDS screening early diagnosis with treatment provided economic value, while Alzheimer’s, Attention Deficit Hyperactivity Disorder, Cardiovascular Creutzfeldt-Jakob Mood Disorder (depression) were not to have value. The current evidence is insufficient determine if for Sleep Apnea provides

Amyotrophic lateral sclerosis was once thought to be caused by persistent viral infection, partly because some patients with transmissible Creutzfeldt-Jakob disease showed prominent amyotrophy. However, in the past 15 years there has been little interest in the amyotrophy in prion diseases, and the possible link to amyotrophic lateral sclerosis has been eschewed. We analyzed case reports of pri...