purpose post exercise proteinuria and increased urinary gamma-glutamyl transferase (ggt) levels can be indicative of exercise-induced renal damage. the aim of this investigation is to study the effect of one session of intensive training on renal damage markers and compare their values to those 6 hours after training. methods in this cross-sectional study with pre- and post-test design, 10 elit...

this study evaluates the effect of preoperative increased level of serum creatinine (cr) on early outcomes after coronary artery bypass graft surgery (cabg). 1140 patients who underwent cabg in our center were studied. patients with cr >2.25 mg/dl or preoperative dialysis and who had off-pump operations were excluded. group 1 consisted of 892 patients with normal cr (0.5-1.2 mg/dl) and group 2 ...

objective(s):bradykinin is a part of the kinin-kallikreinsystem which is involved in ischemia-reperfusion injury via b1 and b2 receptors.noscapine is a non-competitive antagonist of bradykinin receptors. noscapine has been reported to to be able to protect some organs against ischemia-reperfusion injury but its effect on renal ischemia-reperfusion injury (rir) in rats is unknown. therefore, the...

The goal of this review is to present a comprehensive survey of the many intriguing facets of creatine (Cr) and creatinine metabolism, encompassing the pathways and regulation of Cr biosynthesis and degradation, species and tissue distribution of the enzymes and metabolites involved, and of the inherent implications for physiology and human pathology. Very recently, a series of new discoveries ...

Plasma urea and creatinine concentrations and urea and creatinine clearances and excretion were measured in a sample of 40 infants of 25*5-33 weeks' gestation, birth weight 720-2000 g, between the ages of 0 5 and 33 days. Creatinine excretion rate was between 60 and 120 gmol/kg/day in the first five postnatal weeks (mean 90.5) and was independent of sex or growth retardation. This can be used i...

to evaluate the value of random urinary protein creatinine ratio in prediction of 24h proteinuria in hypertensive pregnancies. method: random urine samples and routine 24h urine collections were collected from hypertensive pregnant women (n=100). reliability of random urinary protein-creatinine ratio was assessed by receiver operator characteristic (roc) curve to detect significant proteinuria ...

objective: diabetic nephropathy is a major diabetes complication. arterial resistance index (ri) may predict deterioration in kidney function. this study was designed to compare renal arterial ri in different stages of renal function according to glomerular filtration rate (gfr), serum creatinine level and proteinuria. materials and methods: in a cross-sectional study on 81 diabetic patients in...

background: simvastatin is a widely used medication in cardiac care. here we evaluate the role of atp sensitive potassium (katp) channels in simvastatin induced renal protection after renal ischemia/reperfusion (i/r) injury.    methods: a total of 81 male wistar rats, were treated with simvastatin (10 and 20mg/kg/day gavage, one week). some groups received glibenclamide (katp channel inhibitor ...

background: rupture of fetal membranes can occur at any gestational age. premature rupture of membranes (prom) means rupture of fetal membranes before the onset of labor. objective: the purpose of this study was to evaluate and compare the reliability of the vaginal washing fluid urea and creatinine for the diagnosis of prom and to determine cut-off values. materials and methods: a total of 179...

background assessment of glomerular filtration rate (gfr) by common creatinine-based methods is potentially inaccurate in patients with cirrhosis. cirrhotic patients have several underlying conditions that contribute to falsely low serum creatinine concentrations, even in the presence of moderate to severe renal impairment. therefore creatinine-based methods usually overestimate true gfr in the...