We report a patient with an initial diagnosis of small cell lung cancer treated with prophylactic cranial irradiation (PCI), who subsequently developed a second primary brain neoplasm within the PCI volume. Pathology review was consistent with astrocytoma, WHO grade IV (Glioblastoma Multiforme). After describing our case, we review the literature on the development of a second brain primary aft...

Chronic subdural hematoma (CSDH) is a common but frequently underinvestigated intra cranial lesion. Most times it is attributed to an obvious or trivial head injury, but it possibly may also be a presenting feature of a more serious underlying pathology. This article highlights three patients who presented with CSDH with varying underlying pathologies: acute lymphocytic leukaemia and prostate c...

Central skull base osteomyelitis is a rare, but potentially life-threatening disease entity often lacking otologic symptoms or external auditory canal pathology. We present a case of a man in his 70s who had developed cranial nerve deficits with radiographic evidence that was consistent with a tumor due to this uncommon entity. The radiologic findings and our experience are discussed to increas...

Spondylolysis is a common cause of backache and the detection of subtle cases is therefore important. Oblique views considerably increase the detection rate (Appleby and Stabler 1969), but a number of cases require additional views. The 30#{176} oblique cranial tilt view is more reliable than the standard oblique views in detecting spondylolysis as it visualises the pars interarticularis tangen...

Objective The clinical presentation of sphenoid sinusitis can be highly variable. Rarely, sphenoid sinusitis may present with cranial nerve complications due to the proximity of these structures to the sphenoid sinus. Method A case series from Rabin Medical Center and all cases of cranial nerves palsies secondary to sphenoid sinusitis that have been reported in the literature were reviewed. ...

AIM To describe the origin, the course, and relationships of the labyrinthine artery (LA). MATERIAL AND METHODS Thanks to a colored silicone mix preparation, ten cranial bases were examined using x3 to x40 magnification under surgical microscope. RESULTS The LA often arose from the meatal loop of the anterior inferior cerebellar artery (AICA) (90%), or basilar artery (10%). The loop was ext...

AIMS (1) To assess the value of cranial magnetic resonance imaging (MRI) scans in the investigation of girls with central precocious puberty (CPP); and (2) to determine the clinical predictors of abnormal cranial MRI scans in these patients. METHODS A retrospective study of 67 girls diagnosed with CPP who underwent cranial MRI scans at diagnosis. Patients with neurological signs or symptoms a...

The extra-cranial venous system is complex and not well studied in comparison to the peripheral venous system. A newly proposed vascular condition, named chronic cerebrospinal venous insufficiency (CCSVI), described initially in patients with multiple sclerosis (MS) has triggered intense interest in better understanding of the role of extra-cranial venous anomalies and developmental variants. S...

Background: The extra-cranial venous system is complex and not well studied in comparison to peripheral venous system. A newly proposed vascular condition, named chronic cerebrospinal venous insufficiency (CCSVI), described initially in patients with multiple sclerosis (MS) has triggered intense interest in better understanding of the role of extra-cranial venous anomalies and developmental var...

Background: Microvascular ocular cranial nerve palsy can result from diabetes and hypertension and may be increasing with the increase in the incidence of diabetes and hypertension in Nigeria. Objective: This study provides clinical considerations for the neuro-ophthalmic evaluation of diplopic patients with presumed microvascular ocular cranial nerve palsy. Method: A case report is presented o...