Several Computer Interpretable Guidelines (CIGs) languages have been proposed by the health community. Even though these CIG languages share common ideas each language has to be provided with his own mechanism of verification. In an earlier work we have shown that a DECLARE model can be used for checking the conformance of a PROforma CIG. In this paper, we show that the same model can also be u...

BACKGROUND The proposed association between Chlamydia pneumoniae (Cpn) infection and wheezing needs further clarification. METHODS Serum samples obtained from 1581 children aged 4 years in a population based cohort were tested for antibodies to Cpn and IgE antibodies to common allergens. Data on environmental factors and disease were collected prospectively from birth. RESULTS The occurrenc...

Regulatory changes in the use of some second-generation anticoagulant rodenticides in parts of North America may result in expanded use of first-generation anticoagulant rodenticides (FGARs). Recent toxicological studies with captive raptors have demonstrated that these species are considerably more sensitive to the FGAR diphacinone than traditional avian wildlife test species (mallard, bobwhit...

In this paper, we first demonstrate how a coloured Petri nets (CPN) model can be used to capture requirements for a considered example system, an elevator controller. Then, we show how this requirements-level CPN model is transformed into a design-level object-oriented CPN model, which is structurally and conceptually closer to class diagrams and object-oriented programming languages. The CPN m...

OBJECTIVE The relationship between Chlamydia pneumoniae (Cpn) infection and arterial measures of preclinical atherosclerosis has remained controversial. Because atherogenesis begins in early life, we examined whether carotid and aortic intima-media thickness (IMT) and brachial artery endothelial function are associated with Cpn seropositivity in children. METHODS AND RESULTS Cpn-specific IgG ...

Semi-supervised classification uses a large amount of unlabeled data to help a little amount of labeled data for designing classifiers, which has good potential and performance when the labeled data are difficult to obtain. This paper mainly discusses semi-supervised classification based on CPN (Counterpropagation Network). CPN and its revised models have merits such as simple structure, fast t...

Little is known about the molecular development and heterogeneity of callosal projection neurons (CPN), cortical commissural neurons that connect homotopic regions of the two cerebral hemispheres via the corpus callosum and that are critical for bilateral integration of cortical information. Here we report on the identification of a series of genes that individually and in combination define CP...

Callosal projection neurons (CPN) are a diverse population of neocortical projection neurons that connect the two hemispheres of the cerebral cortex via the corpus callosum. They play key roles in high-level associative connectivity, and have been implicated in cognitive syndromes of high-level associative dysfunction, such as autism spectrum disorders. CPN evolved relatively recently compared ...

The rise of enterprise resource planning (ERP) systems has been a major event in the software industry and it became solution for most enterprises to manage their data business processes. Successful ERP implementations can reduce costs by improving efficiency then lead improved company performance better competitive edge. Despite these benefits age existing several decades still high percentage...

Despite widespread use and benefit, there are growing concerns regarding hazards of second-generation anticoagulant rodenticides to non-target wildlife which may result in expanded use of first-generation compounds, including chlorophacinone (CPN). The toxicity of CPN over a 7-day exposure period was investigated in American kestrels (Falco sparverius) fed either rat tissue mechanically-amended...