We have used temperature-dependent single molecule force spectroscopy to stretch covalently anchored carboxymethylated amylose (CMA) polymers attached to an amino-functionalized AFM cantilever. Using an Arrhenius kinetics model based on a Morse potential as a one-dimensional representation of covalent bonds, we have extracted kinetic and structural parameters of the bond rupture process. With 3...

Mass spectrometry is a valuable tool for the analysis and identification of chemical compounds, particularly proteins and peptides. Lichenysins G, the major cyclic lipopeptide of lichenysin, and the non-covalent complex of lichenysins G and 4-ethylguaiacol were investigated with negative ion ESI tandem mass spectrometry. The different fragmentation mechanisms for these compounds were investigat...

We have performed an experimental structure determination of the ordered p(sqrt[3] x sqrt[3])R30 degrees structures of chlorine and iodine on Au{111} using low-energy electron diffraction (LEED). Despite great similarities in the structure of the underlying substrate, which shows only minor deviations from the bulk positions in both cases, chlorine and iodine are found to adsorb in different ad...

In dynamic covalent chemistry, reactions follow a thermodynamically controlled pathway through equilibria. Reversible covalent-bond formation and breaking in process enables the interconversion of products formed under kinetic control to more stable isomers. Notably, enantioselective catalysis transformations has not been reported applied complex molecule synthesis. We describe discovery metal-...

The role of organometallic intermediates during on-surface polymerization via Ullmann coupling was studied on Ag(111). The polymerization progress was monitored by X-ray photoelectron spectroscopy (XPS). Scanning Tunneling Microscopy (STM) was used to characterize organometallic and covalent networks and to identify the temperature regimes for organometallic and covalent bond formation.

C hemistry is an ever expanding ‘‘universe’’ at the microscopic level requiring mastery of the invisible at ever increasing levels of complexity. Starting with atoms, assemblies of a single nucleus and orbiting electrons, the chemist has learned to understand atomic structure through mastery of the principles of electronic configurations. Proceeding to molecules, assemblies of two or more atoms...

Tin-oxo cage ions undergo Sn–C bond cleavage upon (V)UV excitation. Counterions influence further fragmentation, as they form covalent bonds to the cage.

Tetrathiafulvalene on Pt: The enhanced stability of redox active self-assembled monolayers Pt electrodes allows for sensitive electrochemical anion detection assisted by non-covalent halogen bond formation.

The efficient cyclic aminal formation leads to the stereoselective synthesis of corresponding [2+2] macrocycles, for which dynamic covalent nature bond can be controlled under specific conditions.