Objective: To find out the prevalence of congenital birth defects among pediatric patients Sialkot. Methods: A descriptive cross-sectional study was conducted at pediatrics medicine, surgery and obstetrics ward Khawaja Muhammad Safdar Medical College hospital Sialkot Pregnant women irrespective parity were enrolled in study. Demographic variables, detailed history examination before after deliv...

In the first study of its kind, Guillot et al. (2015) have examined the effects of arranged marriages on genetic diversity. From hemophilia and color blindness among British and Russian monarchies, people have long known the potential damaging genetic consequences of inbreeding. But until recently, no one could measure or understand the impact of marriage rules on genetic diversity. Among the t...

Purpose The practice of consanguinity has been culturally preferred in most Arab countries, including Morocco. This behavior leads to an increase genetic abnormalities, such as hypertension and diabetes. paper examines the prevalence determinants first-cousin marriages their impact on diabetes among offspring. Design/methodology/approach Data 882 couples were collected through face-to-face inte...

Consanguineous couples are at increased risk of having a child with a hereditary/congenital disorder. This extra risk is caused by the fact that the child can inherit the same mutated allele from both parents that originates from a common ancestor. First cousin couples are said to have 1.7-2.8% extra risk on top of the background risk that every couple has of having a child with a congenital/he...

There is little information on inbreeding during the critical early years of human existence. However, given the small founding group sizes and restricted mate choices it seems inevitable that intrafamilial reproduction occurred and the resultant levels of inbreeding would have been substantial. Currently, couples related as second cousins or closer (F ≥ 0.0156) and their progeny account for an...