Journal:
:iranian journal of pharmaceutical research
0
ghazal fadaeian biotechnology group, chemical engineering faculty, tarbiat modares university, tehran, iran
seyed abbas shojaosadati biotechnology group, chemical engineering faculty, tarbiat modares university, tehran, iran
hasan kouchakzadeh biotechnology group, chemical engineering faculty, tarbiat modares university, tehran, iran
fazel shokri department of immunology, school of public health, tehran university of medical science, tehran, iran
masoud soleimani department of hematology, faculty of medical science, tarbiat modares university, tehran, iran
herein, 1f2, an anti-her2 monoclonal antibody (mab), was covalently coupled to the surface of 5-fluorouracil (5-fu) loaded bovine serum albumin (bsa) nanoparticles. concerning two different crosslinkers for conjugation of 1f2, maleimide-poly (ethylene glycol)-succinimidyl carbonate (mal-peg5000-nhs) was selected due to its higher conjugation efficiency (23±4 %) obtained in comparison to n-succi...