Objective(s): Dispersive liquid-liquid microextraction coupled with gas chromatography (GC)-flame ionization detector was developed for the determination of valproic acid (VPA) in human plasma. Materials and Methods: Using a syringe, a mixture of suitable extraction solvent (40 µl chloroform) and disperser (1 ml acetone) was quickly added to 10 ml of diluted plasma sample containing VPA (pH, 1....

FeiYangchangweiyan capsule (FY capsule), a traditional Chinese medicinal preparation consisting of three medicinal herbs, has been used to treat bacterial dysentery, acute, and chronic gastroenteritis for several decades. In this study, a novel, convenient, accurate, and valid method was developed by using high-performance liquid chromatography (HPLC) coupled with diode array detection...

Background: Jamu is commonly known as an Indonesian traditional herbal medicine that contains ingredients or derived from plants, animals, minerals, galenic, mixtures of these have been hereditary for medicinal use. Some studies reported the presence chemicals are deliberately added to Jamu. Jamuthat containing usually had a faster healing effect compared do not contain chemicals. cause serious...

Abstract Levamisole is an anthelminthic that was first used as a de-worming agent in humans and animals. It has also been used to treat inflammatory conditions as well as certain types of cancer. Levamisole was discontinued for human use in the early 21st century due to toxic side effects including agranulocytosis and vasculitis. Recently, levamisole was discovered as a cocaine adulterant after...

an ultrasound-assisted surfactant-enhanced emulsification microextra- ction (uaseme) coupled with high performance liquid chromatography-diode array detection has been developed for the extraction and determination of thiopental in serum and urine samples. a simple microextraction method based on emulsification of organic extraction solvent in aqueous sample using an ionic surfactant and withou...

This paper describes potential applications of computer-assisted chemometrics in method development in liquid chromatography. These include modeling of retention (isocratic, gradient, molecular modeling, artificial neural networks), assessment of separation (peak capacity), single and multiple objective optimization approach, advanced optimization algorithms (genetic algorithms, simulated annea...

a simple and rapid microextraction procedure based on dispersive liquid-liquid microextraction (dllme) coupled with gas chromatography-flame ionization detection (gc-fid) was developed for the extraction and analysis of 2-phenylethanol in rose water sample. in the proposed approach, carbon tetrachloride and ethanol were used as extraction and dispersive solvents, respectively. some important pa...

FeiYangchangweiyan capsule (FY capsule), a traditional Chinese medicinal preparation consisting of three medicinal herbs, has been used to treat bacterial dysentery, acute, and chronic gastroenteritis for several decades. In this study, a novel, convenient, accurate, and valid method was developed by using high-performance liquid chromatography (HPLC) coupled with diode array detection...