Results of different types of treatment in 416 adults with chronic idiopathic thrombocytopenic purpura (ITP) were analyzed. Of 368 patients treated with corticosteroids, 278 (77%) achieved complete response (CR ie, normalization of platelet count). However, only 18% of patients had continued complete response (CCR). Results of splenectomy was analyzed in 126 patients, 49% of them achieved CCR a...

Normalization as a layer within neural networks has over the years demonstrated its effectiveness in network optimization across wide range of different tasks, with one most successful approaches being that batch normalization. The consensus is better estimates BatchNorm normalization statistics (μ and σ2) each mini-batch result optimization. In this work, we challenge belief experiment new var...

In this study, we investigated the effects of changes in formant structure of externally presented speech signals on participants’ auditory perception of their own speech output (i.e., feedback) during a word production task. The study involved a novel combination of two previously established research paradigms: (1) sensorimotor adaptation to altered auditory feedback during speech, and (2) ex...

BACKGROUND Growth impairment is a known complication of sickle cell disease. Effects of hydroxyurea (HU) on growth in very young children are not known. METHODS Height, weight, BMI, and head circumference (HC) were compared with World Health Organization (WHO) standards in BABY HUG, a multicenter, randomized, double-blinded, placebo-controlled 2-year clinical trial of HU in 193 children 9 to ...

Thrombocytopenia is defined as a platelet count of less than 150 × 10(3) per µL. It is often discovered incidentally when obtaining a complete blood count during an office visit. The etiology usually is not obvious, and additional investigation is required. Patients with platelet counts greater than 50 × 10(3) per µL rarely have symptoms. A platelet count from 30 to 50 × 10(3) per µL rarely man...

the mel frequency cepstral coefficients are the most widely used feature in speech recognition but they are very sensitive to noise. in this paper to achieve a satisfactorily performance in automatic speech recognition (asr) applications we introduce a noise robust new set of mfcc vector estimated through following steps. first, spectral mean normalization is a pre-processing which applies to t...

The purpose of this study was to determine if the osmoregulatory response in Escherichia coli BW25993 varied depending on the solute used to cause osmotic stress, as measured by β-galactosidase enzyme activity. β-galactosidase enzyme activity was measured in E. coli BW25993 after osmotic shock with NaCl or sucrose for 2 hours. β-galactosidase activity was normalized against number of colony for...

In research areas such as decision support systems, one of the crucial features is the ability to automatically explain decisions. However, this ability does not typically play a large role in computer games. Here, I suggest that this situation will change: research on the automatic generation of explanations will have real import for many types of computer games. I discuss four possible ways t...