نتایج جستجو برای: cos 7
تعداد نتایج: 648870 فیلتر نتایج به سال:
Soil is a major contributor to the biosphere–atmosphere exchange of carbonyl sulfide (COS) and carbon monoxide (CO). COS is [..1 ]a tracer to quantify terrestrial photosynthesis based on the [..2 ]coupled leaf uptake of COS and [..3 ]CO2, but [..4 ]such use requires separating soil COS flux[..5 ], which is unrelated to photosynthesis, from ecosystem COS uptake. For CO, soil is a [..6 ]significa...
The nonstructural protein 2C is highly conserved among picornaviruses and plays an important role in the assembly of mature virions, membrane association, and viral RNA synthesis. The investigation of other potential functions of nonstructural protein 2C from avian encephalomyelitis virus (AEV) resulted in identifying for the first time that the protein 2C is involved in apoptosis. Expression o...
JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML), a demyelinating disease of the central nervous system in immunocompromised patients. Study PML-type JCPyV vitro has been limited due to difficulty efficient propagation virus cultured cells. In this study, we carried out long term cultivation COS-7 cells (designated as COS-IMRb cells) transfected with PML type M1-I...
ژن درمانی با استفاده از روش هدف گیری ژنی (gene targeting) یکی از بهترین روشهای درمان نقائص ژنتیکی نظیر بتا تالاسمی می باشد. بیماری بتا تالاسمی در اثر کاهش یا فقدان سنتز زنجیره بتا گلوبین به وجود می آید. یکی از روشهای درمان موثر برای این بیماری ژن درمانی توسط حامل های لنتی ویروسی می باشد. ظرفیت حامل های لنتی ویروس حدود 10 کیلو باز است. هدف از این تحقیق طراحی و ساخت حامل لنتی ویروس های نوترکیب فا...
A novel model for the regulation of cell excitability has recently been proposed. It originates from the observation that the background K(+) channel K2P1 (TWIK1) may be silenced by sumoylation in Xenopus oocytes and that inactivation of the putative sumoylation site (mutation K274E) gives rise to robust current expression in transfected COS-7 cells. Here, we show that only the mutation K274E, ...
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