BACKGROUND Coronary artery spasm plays an important role in the pathogenesis of vasospastic angina, and contributes to the development of several acute coronary syndromes. Endothelial nitric oxide synthase (ecNOS) catalyzes the synthesis of nitric oxide, which regulates vascular tone, and may be related to coronary vasospasm. The present study investigated whether coronary spasm is related to p...

Coronary artery spasm after coronary artery bypass grafting (CABG) is a rarephenomenon often resulting in heart failure. We report a case of 56-yearr-old male, who had coronary artery spasm after CABG, which was successfully treated with intracoronary injection of nitroglycerine and heparin.

The spontaneous occurrence of diffuse three vessel coronary artery spasm was documented during routine coronary angiography in three patients with a history of variant angina. Quantitative angiographic analysis of 18 arterial segments demonstrated that the mean luminal diameter of 1.47 mm during spasm increased to 2.47 mm after the administration of nitroglycerin (p less than 0.0001). The under...

A 50-year-old man suffering from recurrent chest pain accompanied by transient ST-segment elevation developed spasm of the left anterior descending coronary artery after receiving ergonovine maleate. During spontaneous chest pain, thermodilution coronary sinus blood flow fell from 96 ml/min to 46 ml/min, while the coronary sinsu arteriovenous oxygen difference widened from 9.82 volumes percent ...

New York, McGraw-Hill, 1970, p 156 44. Prinzmetal M, Kennamer R, Merliss R, Wada T, Bor N: Angina pectoris. I. A variant form of angina pectoris. Am J Med 27: 375, 1959 45. Dhurandar RW, Watt DL, Silver MD, Trimble AS, Adelman AG: Prinzmetal's variant form of angina with arteriographic evidence of coronary arterial spasm. Am J Cardiol 30: 902, 1972 46. Oliva PB, Potts DE, Pluss RG: Coronary art...

BACKGROUND We reported less provoked spasm in the left circumflex artery (LCX) by acetylcholine testing compared with the left anterior descending artery (LAD) and right coronary artery (RCA), so we investigated the clinical characteristics of provoked spasm in the LCX by ergonovine (ER) testing.Methods and Results:We retrospectively analyzed 1,185 consecutive cases of intracoronary ER testing ...

Spasm of the radial artery is the most important cause of failure to perform coronary angiography via the transradial approach. Spasmolytic cocktail may prevent radial artery spasm but is relatively contraindicated in patients with aortic stenosis or diminished left ventricular function. In this case report we describe a recently published technique to overcome severe radial spasm during transr...

36:97–100 5. Briard C, Corat P, Commin P, Chollet A, Menasche P, Echter E: Coronary artery spasm during non-cardiac surgical procedure. Anaesthesia 1983; 38:467–70 6. Buffington CW, Ivey TD: Coronary artery spasm during general anesthesia. ANESTHESIOLOGY 1981; 55:466–9 7. Skarvan K, Graedel E, Hasse J, Stulz P, Pfister M: Coronary artery spasms after coronary bypass surgery. ANESTHESIOLOGY 1984...

Postoperative coronary arterial spasm is a rare but potentially fatal complication. A 51-year-old male patient with a history of a reactive ergonovine stress test coronary angiogram developed refractory coronary artery spasm after undergoing minimally invasive direct coronary artery bypass grafting of the left anterior descending coronary artery. The patient was successfully managed with rapid ...

Variant angina, defined as spontaneous angina pectoris associated with transient ST-segment elevation, is usually caused by episodic coronary spasm. At present, coronary artery spasm is a reversible coronary stenosis that limits coronary blood flow under resting conditions. Prinzmetal first described this type of angina pectoris as a distinct entity in 1959. Although several hypotheses have bee...