Coronary heart disease (also called CHD) is sometimes called coronary artery disease. A coronary artery is a blood vessel that carries blood to your heart. Arteries are like narrow tubes. A fatty substance called plaque can build up in your arteries, blocking or slowing the flow of blood and oxygen through them. This can happen in any artery, but when it happens in the coronary arteries, your h...

BACKGROUND An excessive rate of cardiac death is a well-known feature of renal failure. Coronary heart disease is frequent and the possibility has been raised that the natural history of the coronary plaque is different in uraemic patients. We assessed the morphology of coronary arteries in patients with end-stage renal failure and compared them with coronary arteries of matched non-uraemic con...

To study the relationship between the quantitatively assessed coronary artery dimensions and the regional coronary flow reserve as measured by digital subtraction cineangiography, we investigated 17 coronary arteries with a single discrete proximal stenosis and 12 normal coronary arteries before and after intracoronary administration of papaverine. Coronary flow reserve was found to be curvilin...

Although evidence indicates that estrogen replacement therapy reduces risk of coronary heart disease, the mechanism remains unknown. Among the possibilities are that estrogen replacement therapy may 1) inhibit growth of atherosclerotic plaque and 2) decrease the prevalence of transient myocardial ischemia and myocardial infarction by modulating vasomotion in atherosclerotic coronary arteries. U...

Although previous studies demonstrated beneficial effects of estrogen on cardiovascular function, the Women's Health Initiative has reported an increased incidence of coronary heart disease and stroke in postmenopausal women taking hormone replacement therapy. The objective of the present study was to identify a molecular mechanism whereby estrogen, a vasodilatory hormone, could possibly increa...

BACKGROUND Coronary endothelial function is abnormal in patients with established coronary artery disease and was recently shown by MRI to relate to the severity of luminal stenosis. Recent advances in MRI now allow the noninvasive assessment of both anatomic and functional (endothelial function) changes that previously required invasive studies. We tested the hypothesis that abnormal coronary ...

Coronary artery disease (CAD) is a chronic progressive with social significance, result of obstructive or non- atherosclerotic plaque accumulation in the epicardial arteries. CAD one leading causes for deterioration quality life and cardiovascular mortality. has dynamic character its major clinical presentations are: acute coronary syndromes / STEMI, NSTEMI, UA/ syndromes. In this case report w...

conclusions the pattern and number of vessels involved were similar in both groups. based on common prevalence of traditional risk factors among two groups, planning for lifestyle changes is recommended. results of the 112 patients, 51 (45.5%) were in group a and 61 (54.5%) were in group b with mean age of 37.6 ± 4.4 and 63 ± 8.5, respectively. no significant statistical differences were found ...

Kawasaki disease (KD) is an acute vasculitis syndrome of unknown etiology. It occurs in infants and young children, affecting mainly small and medium-sized arteries, particularly the coronary arteries. Generalized microvasculitis occurs in the first 10 days, and the inflammation persists in the walls of medium and small arteries, especially the coronary arteries, and changes to coronary artery ...

Coronary blood flow was measured by the nitrous oxide method, and cardiac output was measured by the Fick principle, in a series of 31 human subjects with the clinical diagnosis of angina pectoris. Coronary arteriography was carried out on the same subjects as a part of the same procedure, and the extent and severity of the coronary artery lesions was determined. A numerical value was assigned ...