PURPOSE To compare the outcomes after phacoemulsification performed with the AquaLase and phacoemulsification in MicroFlow system, including surgically induced astigmatism (SIA), corneal endothelial cell damage and postoperative recovery of visual acuity. METHODS The cataracts of Lens Opacities Classification System, version III (LOCS III) nuclear grade below 2 were subjected in this study. N...

Purpose: To correlate corneal endothelium cell density with dry eye disease compared to an age-matched control group. Materials and Methods: In this cross-sectional study, a total of 150 eyes of 75 female students aged 19-25 years who did not have any history of eye injuries or eye disease affecting the corneal endothelium cell density, were recruited from KSU Female Campus. They were divided i...

Purpose: To retrospectively estimate the long-term corneal endothelial cell loss in children after perforating corneal trauma and implantation of an iris-fixated anterior-chamber intraocular lens (IOL), either the Artisan aphakia lens or the Artificial Iris Implant, and to compare this corneal endothelial cell loss to that in children who received an Artisan aphakia lens to correct aphakia afte...

OBJECTIVE To compare the efficacy and safety of the intraocular lens (IOL)-shell procedure versus conventional phacoemulsification for the surgical treatment of dense cataracts. METHODS Eighty eyes with dense nuclear cataracts were enrolled in a prospective, randomized controlled study. Patients were assigned to two groups. In Group I, the IOL was traditionally implanted after all nuclear fra...

purpose: to compare the morphology and function of corneal enthothelial cell in early postoperative period after phacoemulsification with infusion or bolus intracameral adrenaline. methods: in this prospective randomized study, 71 eyes of 71 patients scheduled for phacoemulsification were randomly assigned to two groups: one group (31 eyes) received bolus intraocular adrenaline at 1/10,000 conc...

PURPOSE To determine changes in the central endothelium and thickness of grafted corneas and the cumulative probability of developing glaucoma, of graft rejection, and of graft failure 15 years after penetrating keratoplasty. DESIGN Longitudinal cohort study of 500 consecutive penetrating keratoplasties by one surgeon. METHODS Regrafted eyes, fellow eyes of bilateral cases, and patients not...

may have been due to the repeated transfers. In later passages, cell growth slowed down (Fig. 2B). The addition of culture grade EGF to the medium resulted in an improved growth rate (Fig. 2D). Gospodarowicz et al observed similar but much greater effects on bovine endothelial cells. The lower response of murine EGF in this study may be due to the species difference. There has been increasing i...

purpose: to investigate the biomechanical features of transplanted corneas after penetrating keratoplasty (pk), deep anterior lamellar keratoplasty (dalk), and descemet stripping automated endothelial keratoplasty (dsaek) and compare these measurements with those of a normal group. methods: forty-five eyes of 36 patients underwent pk, 23 eyes of 21 patients received dalk using anwar’s big bubbl...

The corneal endothelium is essential for maintaining corneal transparency; therefore, corneal endothelial dysfunction causes serious vision loss. Tissue engineering-based therapy is potentially a less invasive and more effective therapeutic modality. We recently started a first-in-man clinical trial of cell-based therapy for treating corneal endothelial dysfunction in Japan. However, the senesc...

Hyaluronic acid (HA) is a linear polysaccharide naturally found in the eye and therefore is one of the most promising biomaterials for corneal endothelial regenerative medicine. This study reports, for the first time, the development of overrun-processed porous HA hydrogels for corneal endothelial cell (CEC) sheet transplantation and tissue engineering applications. The hydrogel carriers were c...