The effectiveness of radiofrequency (RF) cordotomy of segmental motoneurone pools of the lumbosacral cord in reducing spasticity of decerebrate cats is evaluated. The need for a new form of therapy for clinical spasticity is based upon the limitations of contemporary methods, including surgical and pharmacological techniques. In man, spasticity of spinal origin may be treated effectively by int...

Carcinoma of Bronchus-Garnett et al. MEDICALIJSUHNAL the explanation for the absent lobar perfusion in the other four patients in group 1. However, it is also possible that the bronchial tumour was producing obstructive emphysema, in which case it is postulated that the intra-alveolar pressure may then have been sufficient to prevent the radioactively labelled microemboli from entering the emph...

STUDY DESIGN Examination of hyaluronidase-4 (Hyal-4) expression in a rat spinal cord hemisection model. PURPOSE To determine the status of Hyal-4 expression after hemisection of the spinal cord, and the relationship between its expression and that of chondroitin sulfate proteoglycans (CSPGs). OVERVIEW OF LITERATURE CSPGs are expressed at the site of spinal cord injury and inhibit axon regen...

The effects of oral administration of pentazodne were compared with those of non-DDA analgesics given orally and with those of DDA analgesics given orally and parenterally in patients with intractable pain, over a period of three days while awaiting treatment by percutaneous electrical cordotomy. The dose of pentazodne varied from 25-100 mg four times per day, comparisons being made with the pr...

Intraoperative sonography was performed in 20 children in order to localize intramedullary spinal cord tumors. It provided excellent visualization of the extent and consistency of the tumor before surgical opening of the dura mater. The sonographic findings were used in selecting the site and extent of myelotomy. Intraoperative sonography proved to be a valuable adjunct to spinal cord surgery.