Little is known about cell death in spinal cord tissue following compression injury, despite compression being a key component of spinal injuries. Currently models are used to mimic compression injury in animals and the effects of the compression evaluated by observing the extent and duration of recovery of normal motor function in the days and weeks following the injury. A fibreoptic photoplet...

A rat model study was performed to evaluate the effects of compression of the thoracic spinal cord. Dorsal screw compression of the thoracic spinal cord up to 50% canal diameter was created at T5 (Group A), T5 and T11 (Group B), and T5 and T8 (Group C). Clinical grading (Tarlov criteria), sensory evoked and motor evoked potentials, horse raddish peroxidase neural transport, and microangiography...

Although it is known that aging plays an important role in the incidence and progression of cervical spondylotic myelopathy (CSM), the underlying mechanism is unclear. Studies that used fresh bovine cervical spinal cord report the gray matter of the cervical spinal cord as being more rigid and fragile than the white matter. However, there are no reports regarding the association between aging a...

UNLABELLED Primary spinal involvement in hematological diseases is rare. PURPOSE The purpose of this article is studying diagnostic and treatment strategies in patients with spinal cord primary hematologic tumors causing spinal cord compression syndrome. PATIENTS AND METHODS We report two cases with spinal cord primary hematologic tumors causing spinal cord compression syndrome. One patient...

Spinal cord compression caused by extramedullary hematopoiesis is a rare complication of chronic anemic states, most frequently occurring in patients with beta-thalassemia. We report the MR appearance of extramedullary hematopoiesis resulting in cord compression in a patient with a myelodysplastic syndrome, which was isointense with the spinal cord on T1-weighted images and markedly hypointense...

STUDY DESIGN Histologic changes in the spinal cord caused by progressive spinal kyphosis were assessed using a new animal model. OBJECTIVES To evaluate the effects of chronic compression associated with kyphotic deformity of the cervical spine on the spinal cord. SUMMARY OF BACKGROUND DATA The spinal cord has remarkable ability to resist chronic compression, however, delayed paralysis is so...

OBJECTIVE To evaluate the effect of expansion speed on chronic compressive spinal cord injury in the rat. METHODS Thirty-six Sprague-Dawley rats were divided into four groups: a control group, a group receiving compressor in the C5-C6 epidural space with instant compression (group 1), and two other groups receiving water-absorbing polyurethane polymer sheets with two expansion speeds, which r...