نتایج جستجو برای: cooled egr

تعداد نتایج: 13308  

Journal: :Journal of immunology 2004
John E Harris Kenneth D Bishop Nancy E Phillips John P Mordes Dale L Greiner Aldo A Rossini Michael P Czech

Ag-specific immune tolerance results from the induction of cellular mechanisms that limit T cell responses to selective Ags. One of these mechanisms is characterized by attenuated proliferation and decreased IL-2 production in fully stimulated CD4(+) Th cells and is denoted T cell anergy. We report the identification of the early growth response gene (Egr-2; Krox-20), a zinc-finger transcriptio...

2013
Kui Zhang Jian Cao Ran Dong Jie Du

OBJECTIVES To verify the relationship between Egr-1 and vein graft restenosis and investigate the related mechanisms. METHODS Mouse vein graft models were established in Egr-1 knockout (KO) and wild-type (WT) mice. The vein grafts in the mice were taken for pathological examination and immunohistochemical analysis. The endothelial cells (ECs) were stimulated by using a computer-controlled cyc...

2013
Ling Chu Tiansheng Wang Yongbin Hu Yonghong Gu Zanshan Su Haiying Jiang

The alveolar type II epithelial cell, regarded historically as a key target cell in initial injury by silica, now appears to be important in both defense from lung damage as well as elaboration of chemokines and cytokines. The molecular basis for silica-induced epithelial cell injury is poorly understood. In this study we explored the activation of nuclear factor Egr-1 and related signal pathwa...

2017
Roni Sarkar Subhash C. Verma

Kaposi's sarcoma associated herpesvirus (KSHV) regulates the host cellular environment to establish life-long persistent infection by manipulating cellular signaling pathways, with approximately 1- 5% of cells undergoing lytic reactivation during the course of infection. Egr-1 (Early Growth Response Factor-1) is one such cellular transcription factor, which gets phosphorylated during the lytic ...

Journal: :The Journal of biological chemistry 1992
X M Cao G R Guy V P Sukhatme Y H Tan

Treatment of quiescent primary human fibroblasts with tumor necrosis factor (TNF) alpha, TNF-beta, interleukin-1, interferon (IFN) alpha, IFN beta, or IFN gamma induced Egr-1 mRNA. In primary human fibroblasts TNF-alpha and TNF-beta were mildly mitogenic and IFN alpha and IFN gamma were growth inhibitory. However, in HeLa cells TNF but not IFN induced the expression of Egr-1 mRNA, while both cy...

ژورنال: سوخت و احتراق 2018

در این تحقیق، تاثیر استفاده از یک سامانه EGR بر پارامترهای احتراقی و آلاینده­های NOx و دوده در یک موتور با سوخت بیودیزل بررسی شد. بدین منظور، از یک موتور اشتعال تراکمی تحقیقاتی، دو نوع سوخت دیزل خالص و مخلوط دیزل و بیودیزل (B20)، سه نسبت EGR (0، 10 و 25 درصد) و سه بار 7، 14 و Nm 21 استفاده شد. سوخت مورد استفاده سوخت بیودیزل حاصل از روغن پسماند بود. نتایج حاصل از تحقیق نشان داد که افزودن سوخت بی...

2014
Gautam Bedadala Feng Chen Robert Figliozzi Matthew Balish Victor Hsia

Early Growth response-1 (Egr-1) is a transcription factor that possesses a variety of biological functions. It has been shown to regulate HSV-1 gene expression and replication in different cellular environments through the recruitment of distinct cofactor complexes. Previous studies demonstrated that Egr-1 can be induced by HSV-1 infection in corneal cells but the level was lower compared to ot...

Journal: :Circulation research 2001
H C Lowe R G Fahmy M M Kavurma A Baker C N Chesterman L M Khachigian

Early growth response factor-1 (Egr-1) controls the expression of a growing number of genes involved in the pathogenesis of atherosclerosis and postangioplasty restenosis. Egr-1 is activated by diverse proatherogenic stimuli. As such, this transcription factor represents a key molecular target in efforts to control vascular lesion formation in humans. In this study, we have generated DNAzymes t...

Journal: :international journal of advanced design and manufacturing technology 0
karthikeyan subramanian manager- engine product development ashokleyland- technical center- vellivoiyal chavadi (near new manali town) chennai tamil nadu, india

in the diesel engine exhaust gas recirculation (egr) components, valve and connecting pipes are the critical components and fails often during new engine development. these components are important for meeting nox emissions norms. therefore design of these components should remain robust. but the challenge in design is compact packaging of complete egr components on the engine consequently vibr...

Journal: :تحقیقات موتور 0
محسن قاضی خانی m. ghazikhani محمد شریف زاده m. sharifzadeh امیر ارژنگ نیا a. arjangnia ابوالفضل شریف زاده a. sharifzadeh

in this study a heat exchanger is designed for cooling exhaust gas and an experiment is carried out to investigate the effect of exhaust gas recirculation (egr) temperature on destruction of the fuel’s availability due to combustion processes in idi diesel engine cylinder. to serve this aim an exergy analysis is conducted on the engine cylinder which provides all the availability terms by which...

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