High-resolution electronic interface circuits for transducers with nonlinear capacitive impedance need an operational amplifier, which is stable for a wide range of load capacitance. Such operational amplifier in a conventional design requires a large area for compensation capacitors, increasing costs and limiting applications. In order to address this problem, we present a gain-boosted two-sta...

This paper describes the design of a current mode instrumentation amplifier using second generation current conveyor(CCII). The current mode approach offers several advantages such as high speed, better noise performance and lower power consumption as compared to conventional voltage mode approach. The design is implemented in standard 65 nm CMOS technology. Simulation is done in cadence enviro...

This work shows the generation of an array chirped compressed periodic waves with distributed gain in a nonlinear fibre. In particular, suitable tailoring to vary along longitudinal distance while dispersion and nonlinearity parameters are kept constant. Exact analytical equations using self-similar analysis technique were obtained describe this process. addition, stability these generated is s...

Analysis and simulation are presented of the mismatched load condition for a balanced class-E power amplifier, which is based on 90° hybrids at its input and output. The performances of the 200-Watt balanced class-E amplifier, such as the output power and efficiency, were analyzed and compared to the conventional single-ended class-E power amplifier for the 1:3 VSWR mismatch condition. The simu...

This paper presents a time amplifier design that improves time resolution using an inverter chain delay in SR latches. Compared with the conventional design, the proposed time amplifier has better characteristics such as higher gain, wide range, and small die size. It is implemented using 0.13 μm standard CMOS technology and the experimental results agree well with the theory. key words: time a...

Working memory (WM) is limited in capacity, but it is controversial whether these capacity limitations are domain-general or are generated independently within separate modality-specific memory systems. These alternative accounts were tested in bimodal visual/tactile WM tasks. In Experiment 1, participants memorized the locations of simultaneously presented task-relevant visual and tactile stim...

BACKGROUND Cervical disc arthroplasty (CDA) is a novel motion-preserving procedure that is an alternative to fusion. The Mobi-C disc prosthesis, one of many Food and Drug Administration (FDA)-approved devices for CDA, is the only FDA-approved prosthesis for two-level CDA. Hence, it may allow for improved outcomes compared with multilevel fusion procedures. PURPOSE To critically assess the ava...

The agent 2-chlorodeoxyadenosine (2-CdA) has chemotherapeutic activity in hairy cell leukemia (HCL) and in refractory chronic lymphocytic leukemia (CLL). The cytotoxic activity of 2-CdA requires the intracellular accumulation of 2-CdA nucleotides. Deoxycytidine kinase (dCK) and cytoplasmic 5'-nucleotidase (5'-NT) are the principal enzymes that phosphorylate 2-CdA and dephosphorylate 2-CdA 5'-mo...

Based on the encouraging results of the use of 2-chlorodeoxyadenosine ([2-CdA], cladribine) in patients with advanced, low-grade lymphomas resistant to conventional therapy and the acceptable toxicity profile encountered, we conducted a phase II trial of 2-CdA in patients with untreated indolent lymphomas. Twenty-eight patients with untreated low-grade lymphomas were given 2-CdA at 0.1 mg/kg/d ...