نتایج جستجو برای: contractility
تعداد نتایج: 12131 فیلتر نتایج به سال:
The lymphatic system is a transport system that has important roles in fluid/macromolecule homeostasis, lipid absorption, metastasis and immune function. It accomplishes these roles via the generation of a regulated lymph circulation which is dependent upon valves and pumps to overcome the normal fluid pressure gradients. Lymphatic contractility plays crucial roles in the regulation and generat...
The slope of the stroke work (SW)-pulmonary capillary wedge pressure (PCWP) relation may be negative in congestive heart failure (CHF), implying decreased contractility based on the premise that PCWP is simply related to left ventricular (LV) end-diastolic volume. We hypothesized that the negative slope is explained by decreased transmural LV end-diastolic pressure (LVEDP), despite the increase...
Inotropic effects of electric currents applied during the refractory period have been reported in cardiac muscle in vitro using voltage-clamp techniques. We investigated how electric currents modulate cardiac contractility in normal canine hearts in vivo. Six dogs were instrumented to measure regional segment length, ventricular volume (sonomicrometry), and ventricular pressure. Cardiac contrac...
Cells actively produce contractile forces for a variety of processes including cytokinesis and motility. Contractility is known to rely on myosin II motors which convert chemical energy from ATP hydrolysis into forces on actin filaments. However, the basic physical principles of cell contractility remain poorly understood. We reconstitute contractility in a simplified model system of purified F...
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