purpose: to compare outcomes and recurrence rates of amniotic membrane transplantation (amt) plus intraoperative mitomycin c (mmc) and conjunctival rotational autograft (cra) plus intraoperative mmc in pterygium surgery methods: ninety-two eyes of 92 patients with primary nasal pterygium were enrolled. all patients were randomized to undergo either amt or cra. forty-three patients underwent amt...

PURPOSE The anterior surface of the eye is covered by several physically contiguous but histologically distinguishable epithelial overlying the cornea, limbus, bulbar conjunctiva, fornix conjunctiva, and palpebral conjunctiva. It is important to determine whether the different phenotypes of these epithelia are the result of intrinsic divergence, extrinsic modulation, or a combination of both. B...

Background  To report normal variations of the limbal structures using in vivo laser scanning confocal microscopy. Methods: This was a retrospective study of fourteen eyes from 11 healthy individuals. Confocal imaging of cornea and limbus was performed using Heidelberg Retina Tomograph III Rostock Corneal Module. Results: The typical structure of the palisades of Vogt (POV) was detected ...

INTRODUCTION To the best of our knowledge, this is the first report of a case of conjunctival sarcoidosis that presented as limbal conjunctival hypertrophy and was controlled with topical cyclosporine. CASE PRESENTATION A 70-year-old Asian woman presented with painless limbal conjunctival hypertrophy. An incisional biopsy of the hypertrophic lesion showed noncaseating granulomas that consiste...

Biological effects of nerve growth factor (NGF) are mediated through receptors known as nerve growth factor receptors (NGFR), which include p75 and TrkA. This study was initiated after identifying NGFR as an up-regulated gene in the limbus by cDNA microarray analysis and we postulate that its expression may be indicative of a stem/progenitor cell phenotype. Immunohistochemistry was performed on...

PURPOSES To describe corneal changes seen on in vivo confocal microscopy in patients with total limbal stem cell deficiency and to correlate them with cytological findings. METHODS A prospective case series including 13 eyes (8 patients) with total limbal deficiency was carried out. Stem cell deficiency was diagnosed clinically and by corneal impression cytology. Confocal images of the centra...

The paper is a clinical retrospective analysis of free conjunctival autograft in treatment of pterygia. In period from 1998 until 2006, 47 patients with pterygia were operated using free conjunctival autograft. There were 19 female and 38 male, average age 61 years. In the majority of patients (39/47) it was a primary pterygia. Eight patients were on topical antiglaucoma therapy. Free autograft...

AIM Treatment of recurrent pterygium associated with symblepharon requires both suppression of fibrosis and reconstruction of limbal barrier. To achieve this, human amniotic membrane was transplanted and limbal autografts performed. METHODS Four patients with severe symblepharon resulting from multiple surgeries for pterygium were treated. Human amniotic membrane was obtained at caesarean sec...