OBJECTIVES Congenital cytomegalovirus (CMV) infection is one of the most common intrauterine diseases. In all, 1% of live births is affected by cytomegalovirus infection, while 90% neonates with perinatal infection do not show symptoms of disease. Symptomatic CMV is present in 5-10% of children. Typical clinical signs of CMV infection are microcephalia, mental retardation, progressive major amb...

Sensorineural hearing loss (SNHL) is the most common congenital deficit. As non genetic contributions congenital cytomegalovirus infection (cCMV) is the most frequent cause for this disease. In 10% 20% of patients with sensorineural hearing loss intrauterine infection with cytomegalovirus is diagnosed. Hearing impairment due to CMV can be diagnosed at birth; nevertheless 33% 50% is late-onset l...

Congenital cytomegalovirus (CMV) infection is an important public health problem with approximately 7 in 1,000 newborns infected and consequently at risk for hearing impairment. Newborn hearing screening will fail to detect this hearing impairment in approximately half of the cases because late onset hearing loss is frequent. Hearing impairment has profound impact on cognitive and social develo...

It is almost 150 years since Sir William Wilde (Figure 1), one of the first surgeons to call himself an Otologist, and the father of the celebrated writer, Oscar, considered the causes of deafness in this pessimistic way. The present situation is very different, and in this chapter the causes of hearing impairments and the many strategies that can be utilized to rehabilitate hearing-impaired in...

AIM To assess universal neonatal screening for bilateral hearing impairments averaging 40 dBHL or worse in the better ear, using transient evoked otoacoustic emission screening (TEOAE) testing. METHODS A three year cohort (14,353 infants born from January 1992 to 1995) was screened and subsequently followed up by hearing surveillance methods, including a distraction test screen from 7 months ...

BACKGROUND Congenital cytomegalovirus (CMV) infection is a cause of sensorineural hearing loss (SNHL) in children, but the magnitude of its contribution is uncertain. Quantifying the impact of congenital CMV infection requires an evidence-based assessment using a standard case definition of hearing loss. OBJECTIVES To determine the frequency of bilateral moderate to profound SNHL in children ...

INTRODUCTION According to World Health Organization (WHO) 2001 statistics, hearing disorders are the most common congenital disease, and the incidence rate among high-risk newborns is as much as ten times as high as that in healthy neonates. However, 78% of screening test failures are well-baby nursery babies. The Joint Committee on Infants' Hearing (JCIH) has emphasized the importance of early...

Introduction Deafness is one of the most important sensory disturbances at birth. Hearing loss can affect the development of speaking and learning during life. Early diagnosis and intervention improve language outcome. The  current study aimed to determine the frequency of profound congenital hearing loss in healthy newborn infants in Fars province. Methods In a multicenter prospective study, f...