A pair of monozygotic twin girls is reported with concordance for 3 congenital cardiac abnormalities: (1) secundum atrial septal defect, (2) aneurysm of the membraneous ventricular septum, and (3) electrocardiographic frontal plane left axis deviation. A review of the published materials shows a 9.5 per cent incidence of concordance for congenital heart disease among monozygotic twins. In those...

BACKGROUND Smaller studies and many case series reports indicate that congenital heart defects may be more common in monochorionic twins than in dichorionic twins and singletons. METHODS AND RESULTS We investigated congenital heart defect occurrence in all twins and 5% of all singletons born in Denmark in 1977-2001 and followed through 2006 by linking the Danish Twin Registry and Statistics D...

UNLABELLED The extent of congenital heart disease in Cameroon remains largely unknown. The aim of this study was to determine the occurrence and pattern of congenital heart diseases in the Cardiac Centre of St Elizabeth Catholic General Hospital, situated in a rural area of Cameroon. METHODS Between November 2002 and November 2008, a population of 2 123 patients with suspected cardiac patholo...

CONTEXT AND OBJECTIVE Down syndrome is the most common genetic disorder, affecting 1/700 live births. Among the clinical findings, one constant concern is the high prevalence of congenital heart disease. The objective of this study was to determine the prevalence and profile of congenital heart disease among patients attended at a Down syndrome outpatient clinic in southern Brazil between 2005 ...

Introduction: Congenital vomer agenesis is an extremely rare condition in which the vomer bone does not fully develop, which can lead to septal perforation. Case Report: We report two cases with a defect in the vomer bone in the posteroinferior portion of the septum, found accidentally while performing a pre-operative CT scan for nasal obstruction evaluation. They were diagnosed with congenital...

Congenital heart defects are the most common malformations at birth. Due to the fact that the developmental windows at early stages close rapidly, the aim of this study was to determine the impact of congenital heart defects on the central nervous system at short and medium terms after applying traditional and quantitative electroencephalography techniques and a test of neurodevelopment. Twenty...

The morbid anatomy and histopathology is described as found at necropsy on a 7-year-old coloured girl who suffered from partial defect of the pericardium with prolapse and partial incarceration of the cardiac apex. Because of the absence of any history of illness during life the defect is considered to have been congenital, and because of the lack of any other significant necropsy findings, it ...

Waring, Kajdi and Tappan (1945) described six cases of severe polyuria and polydipsia which showed no response to pitressin therapy. The onset was after birth and the main features were erratic fever, constipation, vomiting and hyper-electrolytaemia without acidosis. The urine was constantly of low specific gravity, and in spite of high fluid intakes it was difficult to maintain hydration. Pitr...