The influence offrusemide on haemodynamic, electrocardiographic, and symptomatic response to exercise was studied in 19 patients with documented coronary artery disease. During the control exercise period all patients experienced angina and showed ST segment depression, accompanied by raised pulmonary artery wedge pressures (PWP). In 12 of these patients 40 mg frusemide was administered intrave...

Left ventricular function was assessed in 10 patients with alcoholic cirrhosis and ascites without clinical evidence of heart disease. In the resting state pulmonary wedge pressure (PWP) was normal (average 9.7 mm Hg), cardiac output (CO) was elevated (average 9.7 L/min) and systemic vascular resistance (SVR) was low (average 825 dynes-sec-cm-5). During infusion of angiotensin in a dose suffici...

BACKGROUND Evidence for longer term exercise delivery for people with Parkinson's disease (PwP) is deficient. AIM Evaluate safety and adherence to a minimally supported community exercise intervention and estimate effect sizes (ES). METHODS 2-arm parallel phase II randomised controlled trial with blind assessment. PwP able to walk ≥100 m and with no contraindication to exercise were recruit...

The so called ”Pierce-Birkhoff Conjecture” asserts that a continuous function h on Rn piecewise polynomial on a finite number of pieces may be written as finitely many Sup and Inf of polynomials. Up to now a positive answer is known for n ≤ 2. In this paper we show that for n = 3 such an Inf-Sup description may be obtained outside an arbitrarily small neighborhood of a finite fixed set of point...

OBJECTIVES We compared the hemodynamic effects of dobutamine and enoximone administration before and after long-term beta-blocker therapy with metoprolol or carvedilol in patients with chronic heart failure (HF). BACKGROUND Patients with HF on beta-blocker therapy may need hemodynamic support with inotropic agents, and the hemodynamic response may be influenced by both the inotropic agent and t...

The PWP method was introduced by Dı́az in 2009 as a technique for measuring indirect influences in complex networks. It depends on a matrix D, provided by the user, called the matrix of direct influences, and on a positive real parameter λ which is part of the method itself. We study changes in the method’s predictions as D and λ vary.

Studies of cardiac performance in hypertension have often been restricted to cardiac output determinations, although the latter alone are inadequate for that purpose. To define the range of cardiac performance in hypertension, the response of left ventricular filling pressure to increased workload (static exercise) was determined in 39 subjects--eight normotensive (NT) volunteers, seven patient...

BACKGROUND Falls amongst people with Parkinson's (PwP) result in significant disability and reduced quality of life. There is emerging evidence that exercise-based and physiotherapeutic interventions are of benefit for improving fall risk factors, such as balance. However, the benefit, in terms of preventing falls, is mixed. The development of effective interventions has been identified as the ...

Left ventricular function was assessed in 10 patients with alcoholic cirrhosis and ascites without clinical evidence of heart disease. In the resting state pulmonary wedge pressure (PWP) was normal (average 9.7 mm Hg), cardiac output (CO) was elevated (average 9.7 L/min) and systemic vascular resistance (SVR) was low (average 825 dynes-sec-cm-5). During infusion of angiotensin in a dose suffici...

Stability Analysis and Controller Synthesis for a Class of Piecewise Smooth Systems Behzad Samadi, Ph.D. Concordia Unviersity, 2008 This thesis deals with the analysis and synthesis of piecewise smooth (PWS) systems. In general, PWS systems are nonsmooth systems, which means their vector fields are discontinuous functions of the state vector. Dynamic behavior of nonsmooth systems is richer than...