نتایج جستجو برای: combination drug eluting stents

تعداد نتایج: 937366  

2010
Mehmet Cilingiroglu Steven R Bailey

Drug-eluting stents are considered a breakthrough in the treatment of coronary artery disease owing to their ability to reduce rates of restenosis and the subsequent need for target lesion revascularization. The literature has limited reports of long-term results of drug-eluting stent implantation with respect to vascular integrity and coronary endothelial function. Thus, we review the currentl...

Journal: :Circulation 2007
Gregg W Stone Stephen G Ellis Antonio Colombo Keith D Dawkins Eberhard Grube Donald E Cutlip Mark Friedman Donald S Baim Joerg Koglin

BACKGROUND Drug-eluting stents compared with bare metal stents (BMS) may increase late stent thrombosis (ST), although an accompanying increase in the rates of death and myocardial infarction (MI) has not been observed. We hypothesized that the prevention of restenosis-related adverse events by drug-eluting stents might offset some or all of the excess risk from ST. METHODS AND RESULTS We ana...

2014
Stephan Windecker Stefan Stortecky Giulio G Stefanini Bruno R daCosta Anne Wilhelmina Rutjes Marcello Di Nisio Maria G Siletta Ausilia Maione Fernando Alfonso Peter M Clemmensen Jean-Philippe Collet Jochen Cremer Volkmar Falk Gerasimos Filippatos Christian Hamm Stuart Head Arie Pieter Kappetein Adnan Kastrati Juhani Knuuti Ulf Landmesser Günther Laufer Franz-Joseph Neumann Dimitri Richter Patrick Schauerte Miguel Sousa Uva David P Taggart Lucia Torracca Marco Valgimigli William Wijns Adam Witkowski Philippe Kolh Peter Juni

OBJECTIVE To investigate whether revascularisation improves prognosis compared with medical treatment among patients with stable coronary artery disease. DESIGN Bayesian network meta-analyses to combine direct within trial comparisons between treatments with indirect evidence from other trials while maintaining randomisation. ELIGIBILITY CRITERIA FOR SELECTING STUDIES A strategy of initial ...

Journal: :Arquivos brasileiros de cardiologia 2012
Celso Kiyochi Takimura Ii-sei Watanabe Francisco Rafael Martins Laurindo Paulo Sampaio Gutierrez Vera Demarchi Aiello Spero Penha Morato Pedro Alves Lemos Neto

BACKGROUND Fast post-implantation stent endothelialization is desirable for theoretically reducing the possibility of stent thrombosis. OBJECTIVE To evaluate the extent of sirolimus-eluting stent strut endothelialization (delivered from the luminal and abluminal aspects or abluminal aspect only) in the iliac arteries of rabbits. METHODS The iliac arteries of 10 rabbits were implanted with f...

Journal: :Journal of biomedical materials research. Part B, Applied biomaterials 2008
Amir Kraitzer Yoel Kloog Meital Zilberman

Coronary artery disease is characterized by a narrowing (stenosis) of the arteries that supply blood to the tissue of the heart. Continued restriction of blood flow manifests itself as angina and ultimately myocardial infarction (heart attack) for the patient. Heart bypass was once the only treatment for this condition, but over the years percutaneous coronary intervention (PCI) has become an i...

2012
Qixia Jiang Chun Liang Zonggui Wu

Drug eluting stents have been implanted worldwide and used in nearly 90% of percutaneous coronary interventions in China. Although many randomized trials have confirmed the efficacy and safety profile of drug eluting stents, they were not powered to detect or exclude the effect of drug eluting stents on rare events such as stent thrombosis. Several mechanisms of very late stent thrombosis have ...

Journal: :The American journal of medicine 2006
Anthony A Bavry Dharam J Kumbhani Thomas J Helton Przemyslaw P Borek Girish R Mood Deepak L Bhatt

PURPOSE Drug-eluting stents are commonly used for percutaneous coronary intervention. Despite excellent clinical efficacy, the association between drug-eluting stents and the risk for late thrombosis remains imprecisely defined. METHODS We performed a meta-analysis on 14 contemporary clinical trials that randomized 6675 patients to drug-eluting stents (paclitaxel or sirolimus) compared with b...

Journal: :Circulation 2004
Jürgen R Sindermann Gabriele Plenz Günter Breithardt

About Safety? To the Editor: Recently, Lemos et al1 and O’Neill and Leon2 provided a balanced overview about drug-eluting stents. The authors nicely addressed the various aspects of this new technology from the economical to the clinical side, including safety and side effects. We would like to supplement another important aspect of safety, the problem of drug interaction, which has not yet rec...

Journal: :Anesthesiology 2007

Journal: :CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2007
Roberto Grilli Paolo Guastaroba Francesco Taroni

BACKGROUND The impact of the use of drug-eluting stents in percutaneous coronary intervention (PCI) on cardiac care is still uncertain. We examined the influence of systemic factors, such as hospital ownership status, organizational characteristics and payment structure, on the use of drug-eluting stents in PCI and the effect on cardiac surgery volume. METHODS We conducted a cross-sectional a...

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