The discovery of a homolog of the retinoblastoma protein (Rb) in a single-celled eukaryote--the alga Chlamydomonas--promises new and surprising insights into Rb's function in cell-cycle regulation.

Gupta Combating HIV/AIDS in India: public-private partnerships are necessary for success 12/27/2006

Combination therapy, a treatment modality that combines two or more therapeutic agents, is a cornerstone of cancer therapy. The amalgamation of anti-cancer drugs enhances efficacy compared to the mono-therapy approach because it targets key pathways in a characteristically synergistic or an additive manner. This approach potentially reduces drug resistance, while simultaneously providing therap...

In combating and regulating underground banking, a choice can be made of roughly two models, the risk model and the assimilation model. The risk model comes down to a complete prohibition of underground banking combined with an active investigation and prosecution policy. In the assimilation model, underground banking is recognised as a form of financial services but at the same time, all rules...

Dental anxiety and subsequent avoidance of dental care and deterioration of oral health pose a significant problem for the dental profession. In an attempt to elucidate preferences of anxious dental patients, we gathered survey data from 121 persons at a small, private liberal arts college in the mid-Atlantic region of the United States. Half of the respondents experienced dental anxiety, and m...

Contents 1. Introduction 1.1. Arid Ecosystems 1.2. Desertification 2. Degradation of natural resources 3. Frame conditions: The importance of scale 4. Defining compartments for feasible approaches 5. Assessment and monitoring of the problem 6. Approaches to combating degradation in arid systems 6.1. Practical steps within the biophysical system 6.1.1 Water resources 6.1.2. Conservation of soils...

Our goal in this paper is to explore two generic approaches to disrupting dark networks: kinetic and nonkinetic. The kinetic approach involves aggressive and offensive measures to eliminate or capture network members and their supporters, while the non-kinetic approach involves the use of subtle, non-coercive means for combating dark networks. Two strategies derive from the kinetic approach: Ta...