We diagnosed colonic cancer using low serum ferritin levels as a clue in two patients with cardiac or cardiopulmonary disease. In the course of the follow-up, the serum ferritin levels decreased to less than 18 ng/mL without significant appearance of iron-deficiency anemia. One patient showed positive immunological fecal occult blood test results whereas the other not. Both patients rejected fu...

Colitis-associated colorectal cancer (CAC) is one of the most common cancers and is closely related to chronic or deregulated inflammation. Helminthic infections can modulate inflammatory responses in some diseases, but their immunomodulatory role during cancer development remains completely unknown. We have analyzed the role of Taenia crassiceps-induced anti-inflammatory response in determinin...

Spirochetes, a genetically and morphologically distinct group of bacteria, are thin, spiral-shaped, and highly motile. They are known causes of several human diseases such as syphilis, Lyme disease, relapsing fever, and leptospirosis. We report a case of colonic spirochetosis in a healthy patient presenting for surveillance colonoscopy. The diagnosis of intestinal spirochetosis was made acciden...

BACKGROUND The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage fluid from patients with colorectal adenomas and carcinomas. METHODS In 45 patients with adenomas, 20 patients with colorectal carcinomas and 3...

Acupuncture is useful for functional bowel diseases, such as constipation and diarrhea. However, the mechanisms of beneficial effects of acupuncture on colonic function have scarcely ever been investigated. We tested the hypothesis that electroacupuncture (EA) at ST-36 stimulates colonic motility and transit via a parasympathetic pathway in conscious rats. Hook-shaped needles were inserted at b...

BACKGROUND Intestinal tuberculosis is a rare disease in western countries, affecting mainly immigrants and immunocompromised patients. Intestinal tuberculosis is a diagnostic challenge, especially when active pulmonary infection is absent. It may mimic many other abdominal diseases. CASE PRESENTATION Here, we report a case of isolated colonic tuberculosis where the initial diagnostic workup w...

depressive disorders are more common among persons with chronic diseases such as inflammatory bowel disease and anti-inflammatory effect of some antidepressants such as amitriptyline has been reported. acetic acid colitis was induced in both reserpinised (depressed) and non-reserpinised (normal) rats. reserpinised groups received reserpine (6 mg/kg, i.p.) one hour prior to colitis induction. th...

Colonic diverticular disease is relatively common in the western hemisphere but a giant colonic diverticulum (GCD) is an unusual finding. A case of GCD with radiographic features suggestive of an appendicular mucocele/ intussusception is reported. At surgery a diagnosis of an appendicular pyocele was considered. The present case makes interesting reading due to it occurring against a background...

Day by day there are new developments in field of colon specific drug delivery system. Colonic drug delivery has gained increased importance not just for the delivery of the drugs for the treatment of local diseases associated with the colon like Crohn’s disease, ulcerative colitis, etc. but also for the systemic delivery of proteins, therapeutic peptides, anti-asthmatic drugs, antihypertensive...

the treatment strategy of colonic injuries is a debatable and highly controversial subject worldwide in various medical centers. the method of treatment of left and .. right colonic injuries, diversity or similarity in their management and particularly differences between the treatment of war-associated injury from other types of colonic damage are among the unsettled issues. the present study ...