introduction: skin resistance is greatly dependent on its collagen amount and nutritional substances such as crude protein that affect the skin collagen can indirectly influence the skin resistance and increase its strength. in this regard, this study aimed to evaluate the effect of in ovo methionine injection on histomorphometry of the skin layers. methods: thirty fertilized eggs of ross 308 b...

To determine the effects of an intact extracellular matrix on collagen synthesis, arterial smooth muscle cells (SMCs) were plated sparsely on a cell-free, SMC-derived matrix and examined the following day. Collagen synthesis during a 5-hour incubation by cells on the matrix was reduced to 67% of the control values obtained from cultures on plastic. Total protein synthesis was unaffected. Treatm...

In this article it is described the composition properties of new synthesis on basis collagen based textile materials, fire-technical classifications recommended fireproof clothes and results experimental tests.

BACKGROUND In chronic liver disease, hepatic stellate cells (HSC) transdifferentiate into myofibroblasts, promoting extracellular matrix (ECM) synthesis and deposition. Stimulation of HSC by transforming growth factor-β (TGF-β) is a crucial event in liver fibrogenesis due to its impact on myofibroblastic transition and ECM induction. In contrast, hepatocyte growth factor (HGF), exerts antifibro...

A line of normal rat embryo fibroblasts was transformed with /V-methyl-W-nitro-N-nitrosoguanidine (a chemical carcinogen), SV40 and polyoma virus (two DMA viruses), and Rous sarcoma virus (an RNA tumor virus). In this study, we report a compari son of the levels of collagen synthesis and procollagen mes senger RNA (mRNA) in 13 lines selected after transformation with one of these agents. Collag...

Introduction: Skin resistance is greatly dependent on its collagen amount and nutritional substances such as crude protein that affect the skin collagen can indirectly influence the skin resistance and increase its strength. In this regard, this study aimed to evaluate the effect of in ovo methionine injection on histomorphometry of the skin layers. Methods: Thirty fertilized eg...

The rates of type I collagen synthesis in sheep lung, tendon, and skin were evaluated during the latter half of fetal development and compared with the levels of type I procollagen mRNA, quantified by molecular hybridization with a type I procollagen specific complementary DNA, and with the activity of total procollagen mRNA measured by in vitro cell-free translation. In the lung and tendon, th...

During developmental growth, collagens are believed to be continuously deposited into an extracellular matrix which is increasingly stabilized by the formation of covalent cross-links throughout life. However, the age-related changes in rates of synthetic and degradative processes are less well understood. In the present study we measured rates of collagen synthesis in vivo using a flooding dos...