objective: the aim of our study is to determine the impact of cochlear implantation on anxiety anddepression in mothers of children with cochlear implant. materials and methods: in a cohort design, 35 mothers of deaf children with cochlear implantion admitted to the clinic of baqiyatallah hospital during january 2008 – january 2010 were selected through systematic sampling. information of demog...

introduction: serum anti endothelial cell antibodies (aecas) play a prominent role in idiopathic sensorineural hearing loss (snhl) in that they induce vascular damage (immune mediated).the of the current study is  to compare aecas in serum and perilymphatic .uid of idiopathic snhl children (<15y) undergoing cochlear implant surgery.methods: this was a cross sectional study performed in the coch...

T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}azetidin-3-ol maleate), a neurotrophic compound newly synthesized for the treatment of Alzheimer's disease, has been found to reduce oxidative stress and exert neuroprotective effects. By assessing the auditory functioning and observing the cochlear sensory epithelia, we investigated whether T-817MA protects the cochlea from inner ear barotra...

ABSTRACT: Over the years, numerous technological advances have taken place in regard to the internal and external components of cochlear implant systems. Such advances include improvements in receiver and electrode design and placement, improvements in external component technology that have brought about downsizing and increased efficiency of externally worn speech processors, and improvements...

Hearing requires the transduction of vibrational forces by specialized epithelial cells in the cochlea known as hair cells. The human ear contains a finite number of terminally differentiated hair cells that, once lost by noise-induced damage or toxic insult, can never be regenerated. We report here that sphingosine 1-phosphate (S1P) signaling, mainly via activation of its cognate receptor S1P2...

Sensory organ damage induces a host of cellular and physiological changes in the periphery and the brain. Here, we show that some aspects of auditory processing recover after profound cochlear denervation due to a progressive, compensatory plasticity at higher stages of the central auditory pathway. Lesioning >95% of cochlear nerve afferent synapses, while sparing hair cells, in adult mice virt...

The most common type of hearing loss results from damage to the cochlea including lost hair cells (HCs) and spiral ganglion neurons (SGNs). In mammals, cochlear HC loss causes irreversible hearing impairment because this type of sensory cell cannot regenerate. The protection from SGN from degeneration has implications for cochlear implant to patients with severe deafness. This review summarizes...

OBJECTIVES The aim of this study was to evaluate the clinical features of cochlear reimplantation due to device failure. METHODS The medical records of 30 patients who had undergone a revision cochlear implantation were retrospectively reviewed. Causes of revision operations, number of electrode channels inserted, and postoperative speech performances were analyzed. RESULTS Device failure (...

The main objective of this study is to provide an overview of the basic mechanisms of blast induced hearing loss and review pharmacological treatments or interventions that can reduce or inhibit blast induced hearing loss. The mechanisms of blast induced hearing loss have been studied in experimental animal models mimicking features of damage or injury seen in human. Blast induced hearing loss ...