background: this study examined the association between incident pulmonary tuberculosis (tb) and social and behavioral characteristics in almaty oblast, kazakhstan from 2012 to 2013. methods: we used a matched case-control design to estimate the role of factors for acquiring pulmonary tb. totally 324 individuals were recruited from sep 2012 to mar 2013. participants included 110 tb index cases ...

introduction: andropause is a common clinical entity of advanced age, with a decline in androgen levels in males. many of the signs of male aging are results of this condition with significant decline in their quality of life and adverse effects on multiple organ systems function. androgen deficiency of the aging male (adam) questionnaire is one of the most applied screening tools for androgen ...

abstract: background and aim:cardio vascular diseases (cvds) are important cause of morbidity and mortality in world wide and constitutes a major public health problem in iran . due to increase of cvd in this contex ,the bjective of this study was to describe the prevalence of cardiovascular risk factors amony gonabad urban population. materials and methods:in this cross sectional study , a tot...

BACKGROUND AND OBJECTIVES Altered levels of coagulation factors have been included among the abnormalities that may increase the risk of venous thromboembolism (VTE) in otherwise healthy subjects. INFORMATION SOURCES According to the studies that have been carried to test this hypothesis only elevated levels of factor VIII and fibrinogen emerged as independent risk factors for VTE. STATE OF...

The liver plays a crucial role in coagulation cascade. Global hemostatic process is profoundly influenced by the presence of liver disease and its complications. Patients with cirrhosis have impaired synthesis of most of the factors involved in coagulation and fibrinolysis process due to a reduced liver function and altered platelet count secondary to portal hypertension. Altered routine tests ...

high blood pressure control (hbpc) is a common goal of who and the world hypertension league (whl). the two important strategies in hbpc are identifying cardiovascular (cvd) risk factors and planning to modify controllable factors. this study was accomplished to determine the cvd risk factors in high blood pressure (hbp) patients of the rural population, residing in the babol region, north of i...

background it is known that risk factors related to neonatal bacterial sepsis are complex. objectives the current study aimed to determine the risk factors of neonatal sepsis. materials and methods this study was conducted on 1023 neonates admitted to neonatal intensive care units (nicus) in south sinai governorate hospitals from january 2010 till september 2014. demographic data of the neonate...

Coagulopathy associated with massive operative blood loss is an intricate, multicellular and multifactorial event. Massive bleeding can either be anticipated (during major surgery with high risk of bleeding) or unexpected. Management requires preoperative risk evaluation and preoperative optimization (discontinuation or modification of anticoagulant drugs, prophylactic coagulation therapy). Int...

In preparation 110 Background: Apart from mediating fibrin deposition, the activated coagulation factors(F) VIIa, Xa and thrombin share the common ability to activate protease-activated receptors (PARs), which are generally assumed to mediate critical functions in angiogenesis and smooth and cardiac muscle physiology. The common ability of coagulation factors to activate the same PARs gives ris...

The clotting process is a dynamic array of multiple processes which can be described in four phases: platelet plug initiation and formation, clotting process propagation by the coagulation cascade, clotting termination by antithrombotic mechanisms and clot removal by fibrinolysis. The liver plays a central role in each of these phases of clotting process, as it synthesizes the majority of coagu...