Rationale: Vascular tissues produce carbon monoxide (CO) via HO-dependent and HO-independent mechanisms; the former in tandem with biliverdin and iron and the latter as a lone product. CO has been shown to function as both a vasoconstrictor and vasodilator; however, factors that dictate the vasoregulatory phenotype of this gas are unknown. Objective: We investigated whether CO-mediated vasocons...

Aim This study was aimed to explore the effects of carboxyhemoglobin on reperfusion injury in hemorrhagic shock, as well as its action time and related mechanisms. Results CO-RBC group showed milder oxidative injury than O2-RBC group. CO reperfusion did not show advantages in functions of kidney and lung during resuscitation. The level of Bax was decreased in CO-RBC group, especially in early...

A bolus method for noninvasive measurement of cardiac output (CO) and mixed venous oxygen content (O2) has been tested against absolute CO and O2 standards in dogs. No statistical differences in CO were found between bolus method and electromagnetic flowmeter measurement comparisons in an 18-dog study in which CO varied from 0. 5 to 3.0 l/min. The SD for all paired differences was 0.14 l/min; h...

The adsorption of fatty acid, kerosene and acid-kerosene on fluorapatite (001) surface were investigated by density functional theory (DFT) calculations. results showed that the single acid could form stable chemisorption O acids bonding with Ca1 site. not be stably adsorbed because H did hydrogen bond PO<sub>4</sub><sup>3-</sup> (O<sub>surf</sub>). For coads...

In purchasing fresh retail meat, the microbiological shelf life, color and general appearance are important features to the consumers. Underlying these features, food safety and product confidence has been increasingly emphasized. Growth of spoilage and pathogenic bacteria is generally reduced by stringent hygienic standards, low storage temperatures and by using modified atmospheres packaging ...

Studies show that the rate of CO oxidation on Pt-group metals at temperatures between 450 and 600 K and pressures between 1 and 300 Torr increases markedly with an increase in the O2/CO ratio above 0.5. The catalytic surfaces, formed at discrete O2/CO ratios >0.5, exhibit rates 2–3 orders of magnitude greater than those rates observed for stoichiometric reaction conditions and similar reactant ...

Enthalpies and entropies have been determined for the reversible binding of O2 and CO to chelated protoheme, a compound having a covalently attached imidazole bound to the iron. The values, based upon 1 atm standard state, are delta HO2 = -14.0 kcal (1 kcal = 4.18 kJ)/mol, delta SO2 = -35 eu, delta HCO = -17.5 kcal/mol, delta SCO = -34 eu, delta H identical to O2 = 21 kcal/mol (dissociation), a...

Tissue hypoxia is a common end product of circulatory shock and a primary target for resuscitation efforts. In this issue Podbregar and Mozina show that thenar tissue O2 saturation (StO2) and mixed venous O2 saturation (SvO2) co-vary in patients in left ventricular failure, but in patients with sepsis StO2 was higher than SvO2. Although StO2 may co-vary with SvO2 they have different determinant...

Using density-functional theory we investigate the interactions and chemical properties of the coadsorption of carbon monoxide and oxygen on ruthenium ~0001!. For the adsorption phases that occur in nature, where CO occupies the top site, we find that with increasing oxygen coverage, the adsorption energy of CO can remain practically unchanged or even exhibit a slight increase. We attribute the...