Changes in conditioning mean arterial pressure (cMAP) selectively alter the set point of arterial baroreceptors and baroreflexes without affecting gain. Changes in smooth muscle tone at constant cMAPs shift the pressure-discharge curves of aortic baroreceptors in a similar manner. Using an in vitro preparation of the rat aortic arch, we tested whether near maximal changes in smooth muscle tone ...

Gene-set-based analysis (GSA), which uses the relative importance of functional gene-sets as units for analysis of genome-wide gene expression data, has exhibited major advantages with respect to greater accuracy, robustness, and biological relevance, over individual gene analysis (IGA), which uses log-ratios of individual genes for analysis. Yet IGA remains the dominant mode of analysis of gen...

We have compared the effects of 50% nitrous oxide and propofol, each administered concurrently with sufentanil, on the amplitudes and latencies of the compound muscle action potential (CMAP) response to transcranial electrical stimulation. Using a crossover design, 12 patients undergoing spinal surgery were exposed to both 50% nitrous oxide and propofol, the latter in a bolus-infusion regimen. ...

OBJECTIVE The purpose of this study was to obtain data on interrater repeatability of the motor nerve conduction velocity (NCV) of the ulnar nerve of different segments, ulnar distal motor latency (DML), and compound muscle action potential (CMAP) amplitudes. DESIGN Twenty-four healthy volunteers were examined in consecutive order. Ulnar motor NCV of different segments, ulnar DML, and CMAP am...

Background and Aim: The present study aimed to use the median nerve Compound Muscle Action Potential (CMAP) amplitude by stimulation at palm instead of Abductor Pollicis Brevis (APB) needle Electromyography (EMG) for determining axonal loss in patients with Carpal Tunnel Syndrome (CTS). Methods Materials/Patients: This was performed on 180 CTS referred Electrodiagnostic (EDX) Center, Poursina H...

Background: 5q-Spinal Muscular Atrophy (SMA) is one of the most prevalent neuromuscular diseases in our country, and still an important cause lethality, due to genetic disease, its severe forms. From a point view, it already known that number copies SMN2 gene drastically influences phenotype inverse relationship with severity disease. Several studies show reduction motor unit counts by differen...

Simons Collaborative Marine Atlas Project (Simons CMAP) is an open-source data portal that interconnects large, complex, and diverse public sets currently dispersed in different formats across Oceanography discipline-specific databases. CMAP designed to streamline the retrieval of custom subsets data, generation visualizations, analyses thus expanding power these potentially underutilized for c...