Erythrocyte choline concentrations were measured in patients with cluster headache and age related control subjects. Concentrations were significantly reduced in the patients with headache both during a cluster period and between clusters, being 58% and 55% of the control value, respectively. After two weeks' treatment with lithium, choline concentrations in the patients with cluster headache i...

Figure 2. Results of Student–Newman–Keuls (SNK) post hoc tests for variables : TOTAL, FUNCTION, EMOTION. Data was grouped into homogeneous subgroups that differ from each other with P< 0.05. Within subgroups no significant differences could be found. CCH, chronic cluster headache; ECHa, episodic cluster headache in the active phase; ECHi, episodic cluster headache outside the active period; MIG...

PURPOSE Cluster headache is one of the most serious types of headache that is accompanied by autonomic parasympathetic symptoms. Its association with hemifacial spasm in the same side had been rarely reported. The aim of this report is describing a case with this association and treatment strategies. CASE REPORT Here we report a 37-year-old female with cluster headache associated with seconda...

We present a study of the general-population prevalence of cluster headache in the Republic of Georgia and discuss the advantages and challenges of different methodological approaches. In a community-based survey, specially trained medical residents visited 500 adjacent households in the capital city, Tbilisi, and 300 households in the eastern rural area of Kakheti. They interviewed all (n = 11...

Cluster headache is the most severe primary headache disorder known. Ten to 20% of cases are medically intractable. DBS of the posterior hypothalamic area has shown effectiveness for alleviation of cluster headache in many but not all of the 46 reported cases from European centers and the eight cases studied at the University of California, San Francisco. This surgical strategy was based on the...

PURPOSE To describe a new, relatively atraumatic method of cauterizing the maxillary artery and its effectiveness in treating cluster headache. MATERIALS AND METHODS Five patients with cluster headache were treated with arterial ligation of certain terminal branches of the external carotid artery. A new, atraumatic method of cauterizing the maxillary artery is described. RESULTS The success...

Following evidence that acupuncture is clinically feasible and cost-effective in the treatment of headache, the UK National Institute for Health and Care Excellence recommends acupuncture as prophylactic treatment for migraine and tension headache. There has thus been expectation that other forms of headache should benefit also. Unfortunately, acupuncture has not generally been successful for c...

INTRODUCTION Cluster headache is a severe hemifacial pain with concomitant symptoms such as lacrimation, conjunctival congestion, and nasal discharge. Peripheral (to be a spectrum of trigeminal autonomic cephalgia) and central (hypothalamus) disorders have been suggested to be involved. Several modalities have been recommended to prevent or alleviate this devastating headache. CASE PRESENTATI...

Cluster headache is a severe headache disorder with considerable impact on quality of life. The pathophysiology of the disease remains poorly understood. With few specific targets for treatment, current guidelines mainly include off-label treatment with medication. However, new targets for possible treatment options are emerging. Calcitonin gene-related peptide (CGRP)-targeted medication could ...

CLINICAL HISTORY A 38-year-old woman reported a history of headache since aged 11 years, occurring about once a month. Triggers included stress and missing a meal, and she described a severe left or right hemicranial throbbing pain with associated nausea, vomiting, photophobia, and phonophobia, but no aura. Attacks lasted up to 3 days. An acetaminophen/aspirin/caffeine combination “dulled” the ...