Endothelium-derived nitric oxide (EDNO) maintains RBF in normal kidneys and to the nonclipped kidney of two-kidney, one-clip (2K, 1C) renovascular hypertensive rats. However, in clipped kidneys with severe renal stenosis, EDNO has been reported not to influence RBF, and it was suggested that low perfusion diminishes the stimulus of shear stress for EDNO synthesis. It was hypothesized that lesse...

BACKGROUND Hawthorn species decreases blood pressure and relaxes precontracted vessels. This study aimed at examining the antihypertensive effect and related mechanisms of hydroalcoholic extract of Crataegus azarolus subspecies aronia fruit in rats with renovascular hypertension. METHODS Six groups of male Sprague-Dawley rats, each containing 6 to 8 rats, were studied. The groups comprised of...

Postoperative angiography for aneurysm surgery is essential in identifying those aneurysms that have been inadequately clipped, allowing for additional corrective surgery. The current standard of reference for the postoperative evaluation of clipped aneurysms is digital subtraction angiography (DSA). However, DSA is an invasive method requiring arterial puncture and intraarterial catheter manip...

Hematocrit can be increased in experimental animals with renal hypertension of two-kidney type. The present study showed that the increased hematocrit was returned to normal by removal of the clipped kidney. The left renal artery was clipped in 13 rabbits with an intact contralateral kidney, and a sham operation was performed in 10 rabbits as a control. After an interval of 10 weeks the left ki...

Although resprouting plays an important role in facilitating persistence of damaged seedlings, the functional attributes of cotyledons and taproots during resprouting of 1-year oak seedlings are not well explored. In this study, cotyledons were removed from Quercus mongolica seedlings to explore resprouting in response to simulated disturbance as a function of shoot clipping, and to examine the...

To examine the interrelation between renin mRNA levels, renin secretion, and blood pressure in rats, we clipped the left renal arteries of rats and measured renin mRNA levels in both kidneys, plasma renin activity, and blood pressure. One and 2 days after clipping, renin mRNA levels increased 3-fold and 4.3-fold in the stenosed kidney and were suppressed to 52% and 26% of controls in the intact...

The present study was aimed at examining the regulation of aquaporin (AQP)-2 water channels in the kidney in two-kidney, one clip (2K1C) hypertension. Rats were made 2K1C hypertensive for 6 weeks, and their expression of AQP2 channel proteins was determined in the clipped and contralateral kidneys. To examine the upstream affecting AQP2 channels, adenylyl cyclase activity was also determined. A...