BACKGROUND Triamcinolone acetonide (TAC) (Kenacort*) is a commonly used synthetic glucocorticoid in today's medical practice. The drug is also a potential agent in inducing cleft palates in rats. This drug has been used to induce cleft palate in the fetus of the pregnant rats to bring out a suitable animal model for human cleft lip and palate. The drug was given intraperitoneally to induce cong...

OBJECTIVES/HYPOTHESIS To find an anatomical measurement of the cleft palate (or a calculated parameter) that predicts the occurrence of velopharyngeal insufficiency (VPI) after palatal cleft repair. STUDY DESIGN Retrospective cohort study. METHODS Charts were reviewed from cleft palate patients who underwent palatoplasty by the Von Langenbeck technique for isolated cleft palate or Bardach t...

BACKGROUND One of the most controversial topics concerning cleft palate is the diagnosis and treatment of velopharyngeal insufficiency (VPI). OBJECTIVE This paper reviews current genetic aspects of cleft palate, imaging diagnosis of VPI, the planning of operations for restoring velopharyngeal function during speech, and strategies for speech pathology treatment of articulation disorders in pa...

background oral cleft is the most common orofacial congenital anomaly among live births. this anomaly at birth is one of the main causes of children disability and mortality.  congenital heart disease (chd) is one of the most common anomalies in oral clefts.  this study aimed to assess the incidence of congenital heart diseases anomalies in newborns with oral clefts. materials and methods this ...

A retrospective study was undertaken of 3100 facial cleft cases in order to analyse and determine the incidence of the isolated cleft of the hard palate. This presented as a very rare occurrence in three different variations, each having specific clinical appearances. The literature search revealed three publications each describing a single isolated hard palate cleft. However, these publicatio...

Cleft lip and palate are birth defects. Children with cleft lip and palate may have problems with quality of voice. The present study compared the perturbation measures of voice (pre and post surgery) in children with cleft lip and palate. Each group included 15 children age ranged 3 to 12 years. They were asked to phonate vowels /a/, /i/, and /u/. Voice samples were recorded and analyzed by us...

Cleft lip and cleft palate are one of the most frequent congenital anomalies worldwide. This study was conducted in order to measure the frequency of cleft lip and palate among live births in Akbar Abadi Hospital. This is a descriptive study, dealing with 57526 cases of live birth out of 59477 medical files in Akbar Abadi Hospital from 2004 to 2008. All the collected data were recorded in speci...

Background: Cleft lip and/or palate are the most common orofacial malformations. Many studies, especially in developed countries have been conducted on this malformation, but in Burkina Faso, data are scarce and they are not specific to children. The aim of this study was to report the epidemiological, clinical and therapeutic aspects of cleft lip and/or palate in children in a low-income count...

OBJECTIVES To evaluate the sensitivity and specificity of ultrasound for detecting prenatal facial clefts in low-risk and high-risk populations. METHODS This study prospectively followed up a non-selected population, namely all pregnant women who underwent routine second-trimester prenatal ultrasound screening in the Utrecht region during the 2-year period from January 2007 to December 2008. ...

Introduction: Children with cleft lip and/or palate are at increased risk of obstructive sleep apnea. The prevalence of obstructive sleep apnea in this population is unknown. The purpose of this study was to assess the frequency of obstructive symptoms and obstructive sleep apnea diagnosis in the cleft population. We hypothesized that obstructive symptoms present more frequently in children wit...